Upper-limb physical activity after distal radius fractures treated operatively or nonoperatively: a secondary analysis of a multicenter randomized trial

Authors

  • Lisa Urup Tønning Department of Orthopedic Surgery, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark https://orcid.org/0000-0003-4666-4622
  • Teemu P Hevonkorpi Department of Orthopaedics, Tampere University Hospital, Tampere, Finland; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland https://orcid.org/0000-0001-5492-1751
  • Antti P Launonen Department of Orthopaedics, Tampere University Hospital, Tampere, Finland https://orcid.org/0000-0002-3125-0171
  • Aleksi Reito Department of Orthopaedics, Tampere University Hospital, Tampere, Finland https://orcid.org/0000-0002-6903-6461
  • Mette S Skjærbæk Department of Orthopedics, Viborg Regional Hospital, Viborg, Denmark
  • Toni Luokkala Department of Hand Surgery, Central Finland Hospital Nova, Jyväskylä, Finland
  • Helle K Østergaard Department of Orthopedics, Viborg Regional Hospital, Viborg, Denmark https://orcid.org/0000-0002-8986-044X
  • Minna K Laitinen Department of Orthopaedics, Helsinki University Hospital, Helsinki, Finland https://orcid.org/0000-0002-9975-0121
  • Bernd Grimm Luxembourg Institute of Health, Luxembourg https://orcid.org/0000-0003-4585-4643
  • Inger Mechlenburg Department of Orthopedic Surgery, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark https://orcid.org/0000-0001-5432-8691
  • Ville M Mattila Department of Orthopaedics, Tampere University Hospital, Tampere, Finland; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

DOI:

https://doi.org/10.2340/17453674.2026.46299

Keywords:

Hand, Wrist, Wrist fracture

Abstract

Background and purpose: While most patients recover well from distal radius fracture, some experience prolonged deficits. We aimed to primarily compare high-intensity upper-limb activity 12 months after operative vs nonoperative treatment of malaligned distal radius fractures and secondarily to assess the impact of fracture alignment and compare activity levels with healthy older adults.
This is a secondary analysis of the Distal Radius Fracture Trial.
Methods: The Distal Radius Fracture Trial was a multicenter, randomized controlled trial. Patients with malaligned distal radius fractures were randomized to operative treatment with a volar locking plate or nonoperative treatment. Patients with well-aligned distal radius fractures constituted a separate non-randomized group. High-intensity upper-limb activity was measured using wrist-worn accelerometers at 3 and 12 months. Healthy subjects were recruited for comparison. Longitudinal analyses were performed using linear mixed models.
Results: 157 patients and 59 healthy controls provided valid accelerometer data. At 12 months patients with malaligned fractures treated operatively had significantly higher high-intensity activity in the affected upper limb than those treated nonoperatively (37 vs 28 min/day; adjusted difference 8.5 min/day, 95% confidence interval [CI] 0.3–17). Fracture alignment was not significantly associated with activity. Compared with healthy subjects, operatively treated patients showed no clear difference (2.7 min/day, CI –8.3 to 14), whereas nonoperatively treated patients demonstrated lower activity levels (12 min/day, CI 4.4–20).
Conclusion: In patients with malaligned distal radius fractures, operative treatment was associated with higher high-intensity upper-limb activity at 12 months than nonoperative treatment. The activity level in operatively treated patients was similar to that observed in healthy older adults.

Downloads

Download data is not yet available.

References

Viberg B, Tofte S, Rønnegaard A B, Jensen S S, Karimi D, Gundtoft P H. Changes in the incidence and treatment of distal radius fractures in adults: a 22-year nationwide register study of 276,145 fractures. Injury 2023; 54(7): 110802. doi: 10.1016/j.injury.2023.05.033.

Wilcke M K T, Hammarberg H, Adolphson P Y. Epidemiology and changed surgical treatment methods for fractures of the distal radius: a registry analysis of 42,583 patients in Stockholm County, Sweden, 2004–2010. Acta Orthop 2013; 84(3): 292-6. doi: 10.3109/17453674.2013.792035.

Hevonkorpi T P, Launonen A P, Huttunen T T, Kannus P, Niemi S, Mattila V M. Incidence of distal radius fracture surgery in Finns aged 50 years or more between 1998 and 2016 - too many patients are yet operated on? BMC Musculoskelet Disord 2018; 19(1): 70. doi: 10.1186/s12891-018-1983-0.

Linnanmäki L, Hevonkorpi T, Repo J, Karjalainen T. Anterior locking plate versus non-operative treatment in different age groups with distal radial fractures: a systematic review and meta-analysis. Hand Surg Eur 2023; 48(6): 532-43. doi: 10.1177/17531934221143636.

Navarro C M, Brolund A, Ekholm C, Heintz E, Ekström E H, Josefsson P O, et al. Treatment of radius or ulna fractures in the elderly: a systematic review covering effectiveness, safety, economic aspects and current practice. PLoS One 2019; 14(3): e0214362. doi: 10.1371/journal.pone.0214362.

Gutiérrez-Espinoza H, Araya-Quintanilla F, Olguín-Huerta C, Gutiérrez-Monclus R, Valenzuela-Fuenzalida J, Román-Veas J, et al. Effectiveness of surgical versus conservative treatment of distal radius fractures in elderly patients: a systematic review and meta-analysis. Orthop Traumatol Surg Res 2022; 108(5): 103323. doi: 10.1016/j.otsr.2022.103323.

Ochen Y, Peek J, van der Velde D, Beeres F JP , van Heijl M, Groenwold R H H, et al. Operative vs nonoperative treatment of distal radius fractures in adults: a systematic review and meta-analysis. JAMA Netw Open 2020; 3(4): e203497-e. doi: 10.1001/jamanetworkopen.2020.3497.

MacDermid J C. The patient-rated wrist evaluation (PRWE)© user manual. Hamilton: McMaster University; 2007 (December).

Hudak P L, Amadio P C, Bombardier C, Beaton D, Cole D, Davis A, et al. Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG). Am J Ind Med 1996; 29(6): 602-8. doi: 10.1002/(SICI)1097-0274(199606)29:6<602::AID-AJIM4>3.0.CO;2-L.

Chung K C, Pillsbury M S, Walters M R, Hayward R A. Reliability and validity testing of the Michigan Hand Outcomes Questionnaire. J Hand Surg Am 1998; 23(4): 575-87. doi: 10.1016/S0363-5023(98)80042-7.

Sliepen M, Lipperts M, Tjur M, Mechlenburg I. Use of accelerometer-based activity monitoring in orthopaedics: benefits, impact and practical considerations. EFORT Open Rev 2019; 4(12): 678-85. doi: 10.1302/2058-5241.4.180041.

Hevonkorpi T P, Launonen A P, Reito A, Skjærbæk M S , Li Y, Luokkala T, et al. Nonoperative treatment versus volar locking plating for distal radius fracture in patients aged 65 years or older (DRIFT trial): a randomized controlled trial. PLoS Med 2025; 22(9): e1004728. doi: 10.1371/journal.pmed.1004728.

Hopewell S, Chan A W, Collins G S, Hróbjartsson A, Moher D, Schulz K F, et al. CONSORT 2025 statement: updated guideline for reporting randomised trials. BMJ 2025; 389(e081123. doi: 10.1136/bmj-2024-081123.

Körver R J, Senden R, Heyligers I C, Grimm B. Objective outcome evaluation using inertial sensors in subacromial impingement syndrome: a five-year follow-up study. Physiol Meas 2014; 35(4): 677-86. doi: 10.1088/0967-3334/35/4/677.

Lipperts M, van Laarhoven S, Senden R, Heyligers I, Grimm B. Clinical validation of a body-fixed 3D accelerometer and algorithm for activity monitoring in orthopaedic patients. J Orthop Translat 2017; 11(19-29. doi: 10.1016/j.jot.2017.02.003.

Schrøder C K, Tønning L U, Tjur M, Kristensen P K, Mechlenburg I. Reference values for daily physical activity measured with accelerometers in a Danish background population between 18 and 80 years of age. Appl Sci 2023; 13(3): 1443. doi: 10.3390/app13031443.

Hevonkorpi T P, Launonen A P, Raittio L, Luokkala T, Kukkonen J, Reito A, et al. Nordic Innovative Trial to Evaluate OsteoPorotic Fractures (NITEP-group): non-operative treatment versus surgery with volar locking plate in the treatment of distal radius fracture in patients aged 65 and over – a study protocol for a prospective, randomized controlled trial. BMC Musculoskelet Disord 2018; 19(1): 106. doi: 10.1186/s12891-018-2019-5.

Wilcke M K, Abbaszadegan H, Adolphson P Y. Patient-perceived outcome after displaced distal radius fractures: a comparison between radiological parameters, objective physical variables, and the DASH score. J Hand Ther 2007; 20(4): 290-8. doi: 10.1197/j.jht.2007.06.001.

Grewal R, MacDermid J C. The risk of adverse outcomes in extra-articular distal radius fractures is increased with malalignment in patients of all ages but mitigated in older patients. J Hand Surg Am 2007; 32(7): 962-70. doi: 10.1016/j.jhsa.2007.05.009.

Batra S, Gupta A. The effect of fracture-related factors on the functional outcome at 1 year in distal radius fractures. Injury 2002; 33(6): 499-502. doi: 10.1016/s0020-1383(01)00174-7.

Hazem D, Grellinger E D, Youn A, Yarboro S, Richter P, Sivananthan S, et al. Practical use of wearable activity measurement devices in orthopaedic surgery: a qualitative analysis of multidisciplinary expert experience. J Clin Med 2026; 15(8): 3009. doi: 10.3390/jcm15083009.

Pasqualini I, Huffman N, Klika A, Kamath A F, Higuera-Rueda C A, Deren M E, et al. Stepping up recovery: integrating patient-reported outcome measures and wearable technology for rehabilitation following knee arthroplasty. J Knee Surg 2024; 37(10): 757-63. doi: 10.1055/a-2315-8110.

Published

2026-07-02

How to Cite

Tønning, L. U., Hevonkorpi, T. P., Launonen, A. P., Reito, A., Skjærbæk, M. S., Luokkala, T., … Mattila, V. M. (2026). Upper-limb physical activity after distal radius fractures treated operatively or nonoperatively: a secondary analysis of a multicenter randomized trial. Acta Orthopaedica, 97, 456–461. https://doi.org/10.2340/17453674.2026.46299

Issue

Section

Publications

Categories

PlumX (by Elsevier) is an altmetrics platform that tracks and visualizes the online attention, usage, captures, citations, and social media engagement.