Evaluation of migration analysis with AI-based CT-RSA and preoperative 3D-planning in total hip arthroplasty

Authors

DOI:

https://doi.org/10.2340/17453674.2025.44948

Keywords:

AI, Arthroplasty, CT-RSA, Hip, Implants, Radiostereometry

Abstract

Background and purpose: Computed tomography (CT) has become a valuable tool for preoperative planning and perioperative, real-time navigation during total hip arthroplasty (THA). CT can also quantify postoperative implant migration without the need for implanted bone markers, making it a promising alternative to the current gold standard radiostereometric analysis (RSA). Our aim was to evaluate the accuracy of preoperative planning and postoperative implant migration of both cup and stem employing AI-based software using 3D CT-images (CT-RSA) compared with conventional RSA.
Methods: 26 patients with primary THA were preoperatively 3D-planned and perioperatively navigated. They were followed and analyzed with AI-based CT-RSA within 2 days postoperatively and at 3, 12, and 24 months. 10 of the patients had implanted tantalum markers at surgery and were also followed up with conventional model-based RSA (MBRSA). The results were compared with CT-RSA. Prosthetic CAD models were used for both conventional RSA and AI-based CT-RSA analysis. Double CT and MBRSA scans were taken to evaluate precision. The preoperative plan was compared with actual perioperatively chosen implants.
Results: AI-based CT-RSA showed consistent migration patterns, with most migration in the first 3 months, which then levelled out. Bland–Altman plots indicated good agreement between MBRSA and AI-based CT-RSA. Overall, there was high correspondence between MBRSA and AI-based CT-RSA in translations, but more divergent rotation results. AI-based CT-RSA precision was consistently slightly better than MBRSA precision. The agreement between planned and actual size of cup was 25 out of 26, and 23 out of 26 for stems.
Conclusion: AI-based CT-RSA demonstrated accuracy comparable to MBRSA, with slightly improved precision and reduced user-dependence. The same system also provided an accurate and predictable preoperative implant plan.

Downloads

Download data is not yet available.

References

Hirano Y, Imai N, Nozaki A, Horigome Y, Suzuki H, Kawashima H. The association of postoperative global femoral offset with total hip arthroplasty outcomes. Sci Rep 2023; 13: 1621. doi: 10.1038/s41598-023-28863-y. DOI: https://doi.org/10.1038/s41598-023-28863-y

Cassidy K A, Noticewala M S, Macaulay W, Lee J H, Geller J A. Effect of femoral offset on pain and function after total hip arthroplasty. J Arthroplasty 2012; 27: 1863-9. doi: 10.1016/j.arth.2012.05.001. DOI: https://doi.org/10.1016/j.arth.2012.05.001

Vorimore C, Innmann M, Mavromatis S, Speirs A, Verhaegen J C F, Merle C, et al. Impact of offset and leg length on functional outcomes post-total hip arthroplasty: how accurate should coronal reconstruction be? J Arthroplasty 2024; 39: S332-S339.e332. doi: 10.1016/j.arth.2024.06.017. DOI: https://doi.org/10.1016/j.arth.2024.06.017

Baghdadi J, Alkhateeb S, Roth A, Jäger M. Cup positioning and its effect on polyethylene wear of vitamin E- and non-vitamin E-supplemented liners in total hip arthroplasty: radiographic outcome at 5-year follow-up. Arch Orthop Trauma Surg 2023; 143: 1679-88. doi: 10.1007/s00402-022-04424-2. DOI: https://doi.org/10.1007/s00402-022-04424-2

Little N J, Busch C A, Gallagher J A, Rorabeck C H, Bourne R B. Acetabular polyethylene wear and acetabular inclination and femoral offset. Clin Orthop Relat Res 2009; 467: 2895-900. doi: 10.1007/s11999-009-0845-3. DOI: https://doi.org/10.1007/s11999-009-0845-3

Colombi A, Schena D, Castelli C C. Total hip arthroplasty planning. EFORT Open Rev 2019; 4: 626-32. doi: 10.1302/2058-5241.4.180075. DOI: https://doi.org/10.1302/2058-5241.4.180075

Eckrich S G, Noble P C, Tullos H S. Effect of rotation on the radiographic appearance of the femoral canal. J Arthroplasty 1994; 9: 419-26. doi: 10.1016/0883-5403(94)90053-1. DOI: https://doi.org/10.1016/0883-5403(94)90053-1

Sariali E, Mueller M, Klouche S. A higher reliability with a computed tomography scan-based three dimensional technique than with a two dimensional measurement for lower limb discrepancy in total hip arthroplasty planning. Int Orthop 2021; 45: 3129-37. doi: 10.1007/s00264-021-05148-5. DOI: https://doi.org/10.1007/s00264-021-05148-5

Geijer M, Rundgren G, Weber L, Flivik G. Effective dose in low-dose CT compared with radiography for templating of total hip arthroplasty. Acta Radiol 2017; 58: 1276-82. doi: 10.1177/0284185117693462. DOI: https://doi.org/10.1177/0284185117693462

Olivecrona H, Maguire G Q Jr, Noz M E, Zeleznik M P, Kesteris U, Weidenhielm L. A CT method for following patients with both prosthetic replacement and implanted tantalum beads: preliminary analysis with a pelvic model and in seven patients. J Orthop Surg Res 2016; 11: 27. doi: 10.1186/s13018-016-0360-7. DOI: https://doi.org/10.1186/s13018-016-0360-7

Brodén C, Sandberg O, Sköldenberg O, Stigbrand H, Hänni M, Giles J W, et al. Low-dose CT-based implant motion analysis is a precise tool for early migration measurements of hip cups: a clinical study of 24 patients. Acta Orthop 2020; 91: 260-5. doi: 10.1080/17453674.2020.1725345. DOI: https://doi.org/10.1080/17453674.2020.1725345

Valstar E R, Gill R, Ryd L, Flivik G, Börlin N, Kärrholm J. Guidelines for standardization of radiostereometry (RSA) of implants. Acta Orthop 2005; 76: 563-72. doi: 10.1080/17453670510041574. DOI: https://doi.org/10.1080/17453670510041574

Angelomenos V, Mohaddes M, Itayem R, Shareghi B. Precision of low-dose CT-based micromotion analysis technique for the assessment of early acetabular cup migration compared with gold standard RSA: a prospective study of 30 patients up to 1 year. Acta Orthop 2022; 93: 459-65. doi: 10.2340/17453674.2022.2528. DOI: https://doi.org/10.2340/17453674.2022.2528

Sandberg O, Tholén S, Carlsson S, Wretenberg P. The anatomical SP-CL stem demonstrates a non-progressing migration pattern in the first year: a low dose CT-based migration study in 20 patients. Acta Orthop 2020; 91: 654-9. doi: 10.1080/17453674.2020.1832294. DOI: https://doi.org/10.1080/17453674.2020.1832294

Brodén C, Sandberg O, Olivecrona H, Emery R, Sköldenberg O. Precision of CT-based micromotion analysis is comparable to radiostereometry for early migration measurements in cemented acetabular cups. Acta Orthop 2021; 10.1080/17453674.2021.1906082: 1-5. doi: 10.1080/17453674.2021.1906082. DOI: https://doi.org/10.1080/17453674.2021.1906082

Scheerlinck T, Polfliet M, Deklerck R, Van Gompel G, Buls N, Vandemeulebroucke J. Development and validation of an automated and marker-free CT-based spatial analysis method (CTSA) for assessment of femoral hip implant migration: in vitro accuracy and precision comparable to that of radiostereometric analysis (RSA). Acta Orthop 2016; 87: 139-45. doi: 10.3109/17453674.2015.1123569. DOI: https://doi.org/10.3109/17453674.2015.1123569

Boettner F, Sculco P, Lipman J, Renner L, Faschingbauer M. A novel method to measure femoral component migration by computed tomography: a cadaver study. Arch Orthop Trauma Surg 2016; 136: 857-63. doi: 10.1007/s00402-016-2442-8. DOI: https://doi.org/10.1007/s00402-016-2442-8

Zhou S, Zhou F, Sun Y, Chen X, Diao Y, Zhao Y, et al. The application of artificial intelligence in spine surgery. Front Surg 2022; 9: 885599. doi: 10.3389/fsurg.2022.885599. DOI: https://doi.org/10.3389/fsurg.2022.885599

Nemati H M, Christensson A, Pettersson A, Németh G, Flivik G. Precision of cup positioning using a novel computed tomography based navigation system in total hip arthroplasty. Medicina (Kaunas) 2024; 60. doi: 10.3390/medicina60101589. DOI: https://doi.org/10.3390/medicina60101589

Christensson A, Nemati H M, Flivik G. Comparison between model-based RSA and an AI-based CT-RSA: an accuracy study of 30 patients. Acta Orthop 2024; 95: 39-46. doi: 10.2340/17453674.2024.35749. DOI: https://doi.org/10.2340/17453674.2024.35749

Huda W, Magill D, He W. CT effective dose per dose length product using ICRP 103 weighting factors. Med Phys 2011; 38: 1261-5. doi: 10.1118/1.3544350. DOI: https://doi.org/10.1118/1.3544350

Behrend H, Giesinger K, Giesinger J M, Kuster M S. The “forgotten joint” as the ultimate goal in joint arthroplasty: validation of a new patient-reported outcome measure. J Arthroplasty 2012; 27: 430-6.e431. doi: 10.1016/j.arth.2011.06.035. DOI: https://doi.org/10.1016/j.arth.2011.06.035

Qinlei Huang. Hands-on tutorial for piecewise linear mixed-effects models using SAS® PROC MIXED. In: St Jude Children’s Research Hospital M, TN, ed. China: PharmaSUG 2015 - 08; 2015.

Bland J M, Altman D G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1: 307-10. DOI: https://doi.org/10.1016/S0140-6736(86)90837-8

Kottner J, Audigé L, Brorson S, Donner A, Gajewski B J, Hróbjartsson A, et al. Guidelines for Reporting Reliability and Agreement Studies (GRRAS) were proposed. J Clin Epidemiol 2011; 64: 96-106. doi: 10.1016/j.jclinepi.2010.03.002. DOI: https://doi.org/10.1016/j.jclinepi.2010.03.002

Critchley O, Callary S, Mercer G, Campbell D, Wilson C. Long-term migration characteristics of the Corail hydroxyapatite-coated femoral stem: a 14-year radiostereometric analysis follow-up study. Arch Orthop Trauma Surg 2020; 140: 121-7. doi: 10.1007/s00402-019-03291-8. DOI: https://doi.org/10.1007/s00402-019-03291-8

Rilby K, Mohaddes M, Nauclér E, Kärrholm J. Similar outcome with a new anteverted or a straight standard stem: a randomized study of 72 total hip arthroplasties evaluated with clinical variables, radiostereometry, and DXA up to 2 years. Acta Orthop 2022; 93: 59-67. doi: 10.1080/17453674.2021.1993606. DOI: https://doi.org/10.1080/17453674.2021.1993606

Bergvinsson H, Zampelis V, Sundberg M, Flivik G. Highly cross-linked polyethylene still outperforms conventional polyethylene in THA: 10-year RSA results. Acta Orthop 2021; 92: 568-74. doi: 10.1080/17453674.2021.1932140. DOI: https://doi.org/10.1080/17453674.2021.1932140

Cho C H, Pijls B G, Abrahams J M, Roerink A, Katembwe R, Baker A, et al. Migration patterns of acetabular cups: a systematic review and meta-analysis of RSA studies. Acta Orthop 2023; 94: 626-34. doi: 10.2340/17453674.2023.24580. DOI: https://doi.org/10.2340/17453674.2023.24580

Pijls B G, Nieuwenhuijse M J, Fiocco M, Plevier J W, Middeldorp S, Nelissen R G, et al. Early proximal migration of cups is associated with late revision in THA: a systematic review and meta-analysis of 26 RSA studies and 49 survival studies. Acta Orthop 2012; 83: 583-91. doi: 10.3109/17453674.2012.745353. DOI: https://doi.org/10.3109/17453674.2012.745353

Bergvinsson H, Sundberg M, Flivik G. Polyethylene wear with ceramic and metal femoral heads at 5 years: a randomized controlled trial with radiostereometric analysis. J Arthroplasty 2020; 35: 3769-76. doi: 10.1016/j.arth.2020.06.057. DOI: https://doi.org/10.1016/j.arth.2020.06.057

Sandberg O H, Kärrholm J, Olivecrona H, Röhrl S M, Sköldenberg O G, Brodén C. Computed tomography-based radiostereometric analysis in orthopedic research: practical guidelines. Acta Orthop 2023; 94: 373-8. doi: 10.2340/17453674.2023.15337. DOI: https://doi.org/10.2340/17453674.2023.15337

Kaptein B L, Pijls B, Koster L, Kärrholm J, Hull M, Niesen A, et al. Guideline for RSA and CT-RSA implant migration measurements: an update of standardizations and recommendations. Acta Orthop 2024; 95: 256-67. doi: 10.2340/17453674.2024.40709. DOI: https://doi.org/10.2340/17453674.2024.40709

Mettler F A Jr, Huda W, Yoshizumi T T, Mahesh M. Effective doses in radiology and diagnostic nuclear medicine: a catalog. Radiology 2008; 248: 254-63. doi: 10.1148/radiol.2481071451. DOI: https://doi.org/10.1148/radiol.2481071451

Ahmed M, Garzanich M, Melaragno L E, Nyirjesy S, Windheim N V, Marquardt M, et al. Exploring CT pixel and voxel size effect on anatomic modeling in mandibular reconstruction. 3D Print Med 2024; 10: 21. doi: 10.1186/s41205-024-00223-0. DOI: https://doi.org/10.1186/s41205-024-00223-0

Øhrn F D, Engseth L H W, Pripp A H, Röhrl S M H, Schulz A. Dose reduction does not impact the precision of CT-based RSA in tibial implants: a diagnostic accuracy study on precision in a porcine cadaver. Acta Orthop 2023; 94: 550-4. doi: 10.2340/17453674.2023.24022. DOI: https://doi.org/10.2340/17453674.2023.24022

Holzer L A, Scholler G, Wagner S, Friesenbichler J, Maurer-Ertl W, Leithner A. The accuracy of digital templating in uncemented total hip arthroplasty. Arch Orthop Trauma Surg 2019; 139: 263-68. doi: 10.1007/s00402-018-3080-0. DOI: https://doi.org/10.1007/s00402-018-3080-0

Mancino F, Fontalis A, Magan A, Plastow R, Haddad F S. The value of computed tomography scan in three-dimensional planning and intraoperative navigation in primary total hip arthroplasty. Hip Pelvis 2024; 36: 26-36. doi: 10.5371/hp.2024.36.1.26. DOI: https://doi.org/10.5371/hp.2024.36.1.26

Reinbacher P, Smolle M A, Friesenbichler J, Draschl A, Leithner A, Maurer-Ertl W. Pre-operative templating in THA using a short stem system: precision and accuracy of 2D versus 3D planning method. J Orthop Traumatol 2022; 23: 16. doi: 10.1186/s10195-022-00634-x. DOI: https://doi.org/10.1186/s10195-022-00634-x

Sariali E, Mauprivez R, Khiami F, Pascal-Mousselard H, Catonné Y. Accuracy of the preoperative planning for cementless total hip arthroplasty: a randomised comparison between three-dimensional computerised planning and conventional templating. Orthop Traumatol Surg Res 2012; 98: 151-8. doi: 10.1016/j.otsr.2011.09.023. DOI: https://doi.org/10.1016/j.otsr.2011.09.023

Zhang B, Li W, Li M, Ding X, Huo J, Wu T, et al. The role of 3-dimensional preoperative planning for primary total hip arthroplasty based on artificial intelligence technology to different surgeons: a retrospective cohort study. Medicine (Baltimore) 2023; 102: e34113. 10.1097/md.0000000000034113. DOI: https://doi.org/10.1097/MD.0000000000034113

Schiffner E, Latz D, Jungbluth P, Grassmann J P, Tanner S, Karbowski A, et al. Is computerised 3D templating more accurate than 2D templating to predict size of components in primary total hip arthroplasty? Hip Int 2019; 29: 270-5. doi: 10.1177/1120700018776311. DOI: https://doi.org/10.1177/1120700018776311

Fontalis A, Yasen A T, Kayani B, Luo T D, Mancino F, Magan A, et al. Two-dimensional versus three-dimensional preoperative planning in total hip arthroplasty. J Arthroplasty 2024; 39: S80-S87. doi: 10.1016/j.arth.2024.05.054. DOI: https://doi.org/10.1016/j.arth.2024.05.054

Published

2025-12-11

How to Cite

Christensson, A., Nemati, H. M., Ydström, K., & Flivik, G. (2025). Evaluation of migration analysis with AI-based CT-RSA and preoperative 3D-planning in total hip arthroplasty. Acta Orthopaedica, 96, 885–892. https://doi.org/10.2340/17453674.2025.44948

Issue

Section

Publications