Lower all-cause 30-day mortality during summer following foot and ankle fracture surgery: a Swedish perioperative register-based study

Authors

  • Elin Lundin Karolinska Institutet, Stockholm, Sweden
  • Jon Karlsson Sahlgrenska Academy, Gothenburg, Sweden
  • Jan G Jakobsson Department of Anaesthesia & Intensive Care, Karolinska Institutet, Stockholm, Sweden

DOI:

https://doi.org/10.2340/17453674.2025.44396

Keywords:

Foot and ankle, Fractures, Mortality, Season variation

Abstract

Background and purpose: An important quality indicator of perioperative care is the all-cause 30-day mortality. Little is known about early mortality after foot and ankle fracture repair. We aimed to assess the all-cause 30-day mortality associated with surgical repair of foot and ankle fractures in Sweden during 2017–2022 and its seasonal variation.
Methods: Foot and ankle fracture patients aged ≥ 18 years registered in the Swedish Perioperative Quality Register (SPOR) between 2017 and June 30, 2022 were included in the analysis (n = 26,404). Patient characteristics, perioperative observations, and early mortality were collected. Seasonal variation was analyzed for summer, autumn, winter, and spring. Perioperative mortality rate and odds ratio (OR) are reported with 95% confidence intervals (CI).
Results: The all-cause 30-day mortality rate was 58 of the 26,404 studied patients (0.22%, CI 0.17–0.28). There was no change in mortality rate over the study period including the COVID-19 pandemic year. Increased adjusted odds ratio (OR) for 30-day mortality was seen among the elderly, age > 80 years, OR 22 (CI 9.2–50), and those with low health status, ASA class 3–4, OR 4.2 (CI 2.3–7.9), while surgery during summer was associated with a lower adjusted OR 0.4 (CI 0.1–0.9).
Conclusion: The all-cause 30-day mortality rate after foot and ankle fracture surgery in Sweden is reassuringly low with expected higher OR for mortality associated with age and health status, while surgery during summer months was associated with lower mortality.

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References

Clench-Aas J, Helgeland J, Dimoski T, Gulbrandsen P, Hofoss D, Holmboe O, et al. Methodological development and evaluation of 30-day mortality as quality indicator for Norwegian hospitals [Internet]. Oslo, Norway: Knowledge Centre for the Health Services at the Norwegian Institute of Public Health (NIPH); 2005 Sep. Report from Norwegian Knowledge Centre for the Health Services (NOKC) No. 04-2005. PMID: 29319970.

Rydberg E M, Wennergren D, Stigevall C, Ekelund J, Möller M. Epidemiology of more than 50,000 ankle fractures in the Swedish Fracture Register during a period of 10 years. J Orthop Surg Res 2023; 18(1): 79. doi: 10.1186/s13018-023-03558-2. DOI: https://doi.org/10.1186/s13018-023-03558-2

Elsoe R, Ostgaard S E, Larsen P. Population-based epidemiology of 9767 ankle fractures. Foot Ankle Surg 2018; 24(1): 34-9. doi: 10.1016/j.fas.2016.11.002. DOI: https://doi.org/10.1016/j.fas.2016.11.002

Happonen V, Kröger H, Kuismin M, Sund R. Ankle fractures in Finland: 118,929 operatively treated between 1987 and 2019. Acta Orthop 2022; 93: 327-33. doi: 10.2340/17453674.2022.2071. DOI: https://doi.org/10.2340/17453674.2022.2071

Spencer E, Berry M, Martin P, Rojas-Garcia A, Moonesinghe S R. Seasonality in surgical outcome data: a systematic review and narrative synthesis. Br J Anaesth 2022; 128(2): 321-32. doi: 10.1016/j.bja.2021.10.043. Epub 2021 Dec 4. PMID: 34872715. DOI: https://doi.org/10.1016/j.bja.2021.10.043

SPOR – Swedish Perioperativt Register. Available from: https://spor.se/ (accessed July 26, 2025).

Holmström B, Enlund G, Spetz P, Frostell C. The Swedish Perioperative Register: description, validation of data mapping and utility. Acta Anaesthesiol Scand 2023; 67(2): 233-9. doi: 10.1111/aas.14174. DOI: https://doi.org/10.1111/aas.14174

Davies J I, Gelb A W, Gore-Booth J, Martin J, Mellin-Olsen J, Åkerman C, et al. Global surgery, obstetric, and anaesthesia indicator definitions and reporting: an Utstein consensus report. PLoS Med 2021; 18(8): e1003749. doi: 10.1371/journal.pmed.1003749. DOI: https://doi.org/10.1371/journal.pmed.1003749

American Society of Anesthesiologists. Statement on ASA Physical Status Classification System. Available from: https://www.asahq.org/standards-and-practice-parameters/statement-on-asa-physical-status-classification-system (accessed July 26, 2025).

Gremillet C, Jakobsson J G. Acute hip fracture surgery anaesthetic technique and 30-day mortality in Sweden 2016 and 2017: a retrospective register study. F1000Res 2018; 7:1009. doi: 10.12688/f1000research.15363.2. DOI: https://doi.org/10.12688/f1000research.15363.1

Sellbrant I, Nellgård B, Karlsson J, Albert J, Jakobsson J G. Anaesthesia practice, quality indices including all-cause 30-day mortality associate to wrist fracture repositioning and surgery in Sweden: a perioperative register-based study 2018–2021. Acta Anaesthesiol Scand 2024; 68(3): 402-9. doi: 10.1111/aas.14358. DOI: https://doi.org/10.1111/aas.14358

Belmont P J Jr, Davey S, Rensing N, Bader J O, Waterman B R, Orr J D. Patient-based and surgical risk factors for 30-day postoperative complications and mortality after ankle fracture fixation. J Orthop Trauma 2015; 29(12): e476-82. doi: 10.1097/BOT.0000000000000328. DOI: https://doi.org/10.1097/BOT.0000000000000328

Xu A L, Raad M, Sotsky R B, Hughes A J, Aiyer A A. Comparative risk stratification for prediction of early postoperative morbidity and mortality after open fixation of periarticular lower extremity fractures. J Clin Orthop Trauma 2022; 31:101940. doi: 10.1016/j.jcot.2022.101940. DOI: https://doi.org/10.1016/j.jcot.2022.101940

Ogawa T, Yoshii T, Higuchi M, Morishita S, Fushimi K, Fujiwara T, et al. Seasonality of mortality and in-hospital complications in hip fracture surgery: retrospective cohort research using a nationwide inpatient database. Geriatr Gerontol Int 2021; 21(5): 398-403. doi: 10.1111/ggi.14153. DOI: https://doi.org/10.1111/ggi.14153

Gundtoft P H, Pedersen A B, Viberg B. Incidence, treatment, and mortality of ankle fractures: a Danish population-based cohort study. Acta Orthop 2025; 96: 203-8. doi: 10.2340/17453674.2025.43006. DOI: https://doi.org/10.2340/17453674.2025.43006

Jammer I, Brandsborg B. How to improve perioperative pathways for the patient and society. Acta Anaesthesiol Scand 2023; 67(2): 126-7. doi: 10.1111/aas.14192. DOI: https://doi.org/10.1111/aas.14192

Kvåle R, Möller M H, Porkkala T, Varpula T, Enlund G, Engerstrôm L, et al. The Nordic perioperative and intensive care registries: collaboration and research possibilities. Acta Anaesthesiol Scand 2023; 67(7): 972-8. doi: 10.1111/aas.14255. DOI: https://doi.org/10.1111/aas.14255

Published

2025-08-07

How to Cite

Lundin, E., Karlsson, J., & Jakobsson, J. G. (2025). Lower all-cause 30-day mortality during summer following foot and ankle fracture surgery: a Swedish perioperative register-based study. Acta Orthopaedica, 96, 601–605. https://doi.org/10.2340/17453674.2025.44396