Pediatric hip disorders are not associated with an increased 10-year revision risk after total hip arthroplasty under the age of 55: results from the Dutch Arthroplasty Register

Authors

  • Michaël P A Bus Department of Orthopedic Surgery, Leiden University Medical Center, Leiden https://orcid.org/0000-0003-0023-6016
  • Maaike G J Gademan Department of Orthopedic Surgery, Leiden University Medical Center, Leiden; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden https://orcid.org/0000-0002-6106-3385
  • Marta Fiocco Department of Biomedical Data Science, section Medical Statistics, Mathematical Institute Leiden University, Leiden, The Netherlands
  • Rob G H H Nelissen Department of Orthopedic Surgery, Leiden University Medical Center, Leiden https://orcid.org/0000-0003-1228-4162
  • Pieter Bas de Witte Department of Orthopedic Surgery, Leiden University Medical Center, Leiden

DOI:

https://doi.org/10.2340/17453674.2024.41342

Keywords:

Arthroplasty, Hip, Paediatric orthopaedics

Abstract

Background and purpose: Developmental dysplasia (DDH) and Legg–Calvé–Perthes disease (LCPD) are common indications for total hip arthroplasty (THA) at a young age, and may be associated with increased revision risk. We aimed to investigate the 10-year cumulative aseptic cup revision and overall revision risk of THA, and investigated whether these are increased compared with THA for primary osteoarthritis (OA) in patients below 55 years.
Methods: All THAs (2007–2019) in patients under the age of 55 for the indications OA, DDH, and LCPD were extracted from the Dutch Arthroplasty register. The 10-year cumulative incidences of aseptic cup failure and overall revision were assessed for the 3 groups, with death as a competing risk. Cox regression analysis was used.
Results: 24,263 THAs were identified: 20,645 (85%) for OA, 3,032 (13%) for DDH, and 586 (2%) for LCPD. The 10-year cumulative revision risk for aseptic cup failure was 3.4% (95% confidence interval [CI] 3.0–3.8) for OA, 3.4% (CI 2.4–3.4) for DDH, and 1.7% (CI 0.2–3.1) for LCPD. The 10-year cumulative overall revision risk was 6.0% (CI 5.6–6.5) for OA, 6.0% (CI 4.9–7.2) for DDH, and 5.1% (2.7–7.5) for LCPD. The multivariable Cox regression analysis for aseptic cup failure yielded hazard ratios of 0.7 (0.5–1.2) for DDH, and 0.8 (0.3–2.1) for LCPD compared with OA. No statistically significant differences for overall revision were found.
Conclusion: THA performed for DDH or LCDP in patients under the age of 55 was not associated with a statistically significant increased risk of aseptic cup revision or overall revision, compared with THA performed for primary OA in the same age group.

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References

Gademan M G J, Van Steenbergen L N, Cannegieter S C, Nelissen R, Marang-Van De Mheen P J. Population-based 10-year cumulative revision risks after hip and knee arthroplasty for osteoarthritis to inform patients in clinical practice: a competing risk analysis from the Dutch Arthroplasty Register. Acta Orthop 2021; 92: 280-4. doi: 10.1080/17453674.2021.1876998.

Thillemann T M, Pedersen A B, Johnsen SP, Søballe K; Danish Hip Arthroplasty Register. Implant survival after primary total hip arthroplasty due to childhood hip disorders: results from the Danish Hip Arthroplasty Registry. Acta Orthop 2008; 79: 769-76. doi: 10.1080/17453670810016830.

Engesaeter I O, Lehmann T, Laborie L B, Lie S A, Rosendahl K, Engesaeter L B. Total hip replacement in young adults with hip dysplasia: age at diagnosis, previous treatment, quality of life, and validation of diagnoses reported to the Norwegian Arthroplasty Register between 1987 and 2007. Acta Orthop 2011; 82: 149-54. doi: 10.3109/17453674.2011.566146.

Eskelinen A, Remes V, Helenius I, Pulkkinen P, Nevalainen J, Paavolainen P. Uncemented total hip arthroplasty for primary osteoarthritis in young patients: a mid-to long-term follow-up study from the Finnish Arthroplasty Register. Acta Orthop 2006; 77: 57-70. doi: 10.1080/17453670610045704.

McAuley J P, Szuszczewicz E S, Young A, Engh C A, Sr. Total hip arthroplasty in patients 50 years and younger. Clin Orthop Relat Res 2004; (418): 119-25. doi: 10.1097/00003086-200401000-00019.

McLaughlin J R, Lee K R. Total hip arthroplasty in young patients. 8- to 13-year results using an uncemented stem. Clin Orthop Relat Res 2000; (373): 153-63. PMID: 10810473.

Greber E M, Pelt C E, Gililland J M, Anderson M B, Erickson J A, Peters C L. Challenges in total hip arthroplasty in the setting of developmental dysplasia of the hip. J Arthroplasty 2017; 32: S38-S44. doi: 10.1016/j.arth.2017.02.024.

Traina F, De Fine M, Sudanese A, Calderoni P P, Tassinari E, Toni A. Long-term results of total hip replacement in patients with Legg–Calve–Perthes disease. J Bone Joint Surg Am 2011; 93: e25. doi: 10.2106/JBJS.J.00648.

Engesaeter L B, Engesaeter I O, Fenstad A M, Havelin L I, Kärrholm J, Garellick G, et al. Low revision rate after total hip arthroplasty in patients with pediatric hip diseases. Acta Orthop 2012; 83: 436-41. doi: 10.3109/17453674.2012.736171.

Girard J, Glorion C, Bonnomet F, Fron D, Migaud H. Risk factors for revision of hip arthroplasties in patients younger than 30 years. Clin Orthop Relat Res. 2011; 469: 1141-7. doi: 10.1007/s11999-010-1669-x.

van Steenbergen L N, Denissen G A, Spooren A, van Rooden S M, van Oosterhout F J, Morrenhof J W, et al. More than 95% completeness of reported procedures in the population-based Dutch Arthroplasty Register. Acta Orthop 2015; 86: 498-505. doi: 10.3109/17453674.2015.1028307.

Keurentjes J C, Fiocco M, Schreurs B W, Pijls B G, Nouta K A, Nelissen R G. Revision surgery is overestimated in hip replacement. Bone Joint Res 2012; 1: 258-62. doi: 10.1302/2046-3758.110.2000104.

Putter H, Fiocco M, Geskus R B. Tutorial in biostatistics: competing risks and multi-state models. Stat Med 2007; 26: 2389-2430. doi: 10.1002/sim.2712.

Team RC. R: A language and environment for statistical computing. Vienna: R Foundation for Statistical Computing; 2008.

de Wreede L C, Fiocco M, Putter H. The mstate package for estimation and prediction in non- and semi-parametric multi-state and competing risks models. Comput Methods Programs Biomed 2010; 99: 261-74. doi: 10.1016/j.cmpb.2010.01.001.

Anthony C A, Wasko M K, Pashos G E, Barrack R L, Nunley R M, Clohisy J C. Total hip arthroplasty in patients with osteoarthritis associated with Legg–Calve–Perthes disease: perioperative complications and patient-reported outcomes. J Arthroplasty 2021; 36: 2518-22. doi: 10.1016/j.arth.2021.02.031.

Chougle A, Hemmady M V, Hodgkinson J P. Long-term survival of the acetabular component after total hip arthroplasty with cement in patients with developmental dysplasia of the hip. J Bone Joint Surg Am 2006; 88: 71-9. doi: 10.2106/JBJS.D.02689.

Lazarinis S, Kärrholm J, Hailer N P. Increased risk of revision of acetabular cups coated with hydroxyapatite. Acta Orthop 2010; 81: 53-9. doi: 10.3109/17453670903413178.

Bayliss L E, Culliford D, Monk A P, Glyn-Jones S, Prieto-Alhambra D, Judge A, et al. The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study. Lancet 2017; 389: 1424-30. doi: 10.1016/S0140-6736(17)30059-4.

Corbett K L, Losina E, Nti A A, Prokopetz J J, Katz J N. Population-based rates of revision of primary total hip arthroplasty: a systematic review. PloS one 2010; 5: e13520. doi: 10.1371/journal.pone.0013520.

Prentice H A, Chan P H, Royse K E, Hinman A D, Reddy N C, Paxton E W. Revision risk in a cohort of US patients younger than 55 undergoing primary elective total hip arthroplasty. J Arthroplasty 2022; 37: 303-11. doi: 10.1016/j.arth.2021.10.014.

Prokopetz J J, Losina E, Bliss R L, Wright J, Baron J A, Katz J N. Risk factors for revision of primary total hip arthroplasty: a systematic review. BMC Musculoskelet Disord 2012; 13: 251. doi: 10.1186/1471-2474-13-251.

Puolakka T J, Pajamaki K J, Halonen P J, Pulkkinen P O, Paavolainen P, Nevalainen J K. The Finnish Arthroplasty Register: report of the hip register. Acta Orthop Scand 2001; 72: 433-41. doi: 10.1080/000164701753532745.

Fevang B T, Lie S A, Havelin L I, Engesaeter L B, Furnes O. Improved results of primary total hip replacement. Acta Orthop 2010; 81: 649-59. doi: 10.3109/17453674.2010.537807.

Furnes O, Lie S A, Espehaug B, Vollset S E, Engesaeter L B, Havelin L I. Hip disease and the prognosis of total hip replacements: a review of 53,698 primary total hip replacements reported to the Norwegian Arthroplasty Register 1987-99. J Bone Joint Surg Br 2001; 83: 579-86. doi: 10.1302/0301-620x.83b4.11223.

Konan S, Duncan C P. Total hip arthroplasty in patients with neuromuscular imbalance. Bone Joint J 2018; 100-B: 17-21. doi: 10.1302/0301-620X.100B1.BJJ-2017-0571.R1.

Queally J M, Abdulkarim A, Mulhall K J. Total hip replacement in patients with neurological conditions. J Bone Joint Surg Br 2009; 91: 1267-73. doi: 10.1302/0301-620X.91B10.22934.

Luther A Z, Clarke N M. Developmental dysplasia of the hip and occult neurologic disorders. Clin Orthop Relat Res 2008; 466: 871-7. doi: 10.1007/s11999-008-0118-6.

Published

2024-08-28

How to Cite

Bus, M. P. A., Gademan, M. G. J., Fiocco, M., Nelissen, R. G. H. H., & de Witte, P. B. (2024). Pediatric hip disorders are not associated with an increased 10-year revision risk after total hip arthroplasty under the age of 55: results from the Dutch Arthroplasty Register. Acta Orthopaedica, 95, 472–476. https://doi.org/10.2340/17453674.2024.41342