Effects of Cyclophosphamide on Mechanical Properties of Bone and Skin in Rats
DOI:
https://doi.org/10.3109/17453677908991284Abstract
The effects of several different doses of cyclophosphamide on weight increase, longitudinal bone growth and mechanical properties of bone, intact skin and skin wounds, were studied in 30 young, male rats. The cytostatic effect was evaluated by counting white blood cells (WBC) in arterial blood at the end of the medication period. Compared with the control animals, the longitudinal bone growth, the mechanical properties of the distal femoral metaphysis and the skin wounds were most noticeably affected by the drug. Diaphyseal torsional strength of the femoral bone and tensile strength of intact skin were less affected.Downloads
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Published
1979-01-01
How to Cite
Wie, H., Engesaeter, L. B., & Beck, E. I. (1979). Effects of Cyclophosphamide on Mechanical Properties of Bone and Skin in Rats. Acta Orthopaedica, 50(6), 629–634. https://doi.org/10.3109/17453677908991284
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Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
