Low-Dose Heparin in Proximal Femoral Fractures: Failure to Prevent Deep-Vein Thrombosis

Authors

  • H. Svend-Hansen
  • V. Bremerskov
  • J. Gøtrich
  • P. Ostri

DOI:

https://doi.org/10.3109/17453678108991763

Abstract

The effect of heparin, 5000 units every 8 hours, on deep venous thrombosis in patients with proximal femoral fractures was investigated in a controlled, double blind, randomised study. Heparin or placebo was administered as soon as possible after the fracture, and before 6 hours had passed, and was continued for 14 days. The diagnosis of deep venous thrombosis was made using daily I125 fibrinogen scans. A total of 130 patients entered the trial and the results were registered on a sequential diagram. This showed that the 0-hypothesis could not be rejected, and that consequently no difference in the frequency of deep-vein thrombosis was detected.

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Published

1981-01-01

How to Cite

Svend-Hansen, H., Bremerskov, V., Gøtrich, J., & Ostri, P. (1981). Low-Dose Heparin in Proximal Femoral Fractures: Failure to Prevent Deep-Vein Thrombosis. Acta Orthopaedica, 52(1), 77–80. https://doi.org/10.3109/17453678108991763