Depressive Effects of Acrylic Cement Components on Bone Metabolism: Isotope Release and Phosphatase Production Studied in Vitro

John Gregor Pedersen; Bjarne Lund; Inge Reimann

doi:10.3109/17453678308992911

Depressive Effects of Acrylic Cement Components on Bone Metabolism: Isotope Release and Phosphatase Production Studied in Vitro

Authors

John Gregor Pedersen
Bjarne Lund
Inge Reimann

DOI:

https://doi.org/10.3109/17453678308992911

Abstract

In vitro methyl methacrylate bone cement components were found to depress the release of radioactive calcium and proline as well as the activity of both alkaline and acid phosphatases. These effects were dose dependent and reached levels observed for dead bone. These observations may reflect part of the pathogenesis of loosening of joint replacements involving the use of bone cement.

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Published

1983-05-15

How to Cite

Pedersen, J. G., Lund, B., & Reimann, I. (1983). Depressive Effects of Acrylic Cement Components on Bone Metabolism: Isotope Release and Phosphatase Production Studied in Vitro. Acta Orthopaedica, 54(6), 796–801. https://doi.org/10.3109/17453678308992911

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Issue

Acta Orthopaedica, Volume 54, Issue 6 (1983)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.