S-100 protein in human articular cartilage

Authors

  • Shigeru Nakamura
  • Toshitaka Nakamura
  • Hajime Kawahara

DOI:

https://doi.org/10.3109/17453678809149398

Abstract

We studied the immunohistochemical distribution of the alpha and beta subunits of S-100 protein in human articular cartilage by the Avidin-Biotin Complex method using monoclonal antibodies against each subunit. Immunostaining for both subunits was detected in chondrocytes in superficial. intermediate, and deep zones of normal articular cartilage. In the matrix, only the superficial zone was stained positively. In arthrotic joints, we detected intense immunostaining in clustered chondrocytes in the hypercellular area. and weak or no immunostaining in isolated chondrocytes in the hypocellular area of articular cartilage.

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Published

1988-01-01

How to Cite

Nakamura, S., Nakamura, T., & Kawahara, H. (1988). S-100 protein in human articular cartilage. Acta Orthopaedica, 59(4), 438–440. https://doi.org/10.3109/17453678809149398