Chemonucleolysis for sciatica A critical review

Authors

  • Alf L. Nachemson
  • Björn Rydevik

DOI:

https://doi.org/10.3109/17453678809149346

Abstract

Inttadiscal injection of chymopapain for the treatment of sciatica due to disc herniation has been used for more than 25 years, but is still under debate. We review the indications, complications, and clinical results, and discuss the tissue effects of chymopapain. The results following surgical disc removal versus chymopapain injection indicate that surgery with removal of the disc hernia through a small laminotomy remains the documented treatment of choice for patients with proven disc herniation and sciatica in whom conservative treatment has failed.

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Published

1988-01-01

How to Cite

Nachemson, A. L., & Rydevik, B. (1988). Chemonucleolysis for sciatica A critical review. Acta Orthopaedica, 59(1), 56–62. https://doi.org/10.3109/17453678809149346

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