Rabbit bone matrix induces bone formation in the athymic rat

Authors

  • Per Aspenberg
  • Karl-Göran Thorngren
  • L. Stefan Lohmander

DOI:

https://doi.org/10.3109/17453678809149362

Abstract

Rabbit and rat bone matrix were implanted in athymic rat muscle, and the bone yield was measured as total calcium content after 4, 6, and 8 weeks. Matrix from both species induced equal amounts of new bone in the athymic rat. In rabbit and normal rat, the xenogenic matrix induced little or no bone formation. Thus, in the case of rabbit and rat, bone induction is species specific due to immunogenic mechanisms. The athymic rat can be used to measure inductive properties of bone matrix from different species.

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Published

1988-01-01

How to Cite

Aspenberg, P., Thorngren, K.-G., & Lohmander, L. S. (1988). Rabbit bone matrix induces bone formation in the athymic rat. Acta Orthopaedica, 59(3), 276–278. https://doi.org/10.3109/17453678809149362

Issue

Acta Orthopaedica, Volume 59, Issue 3 (1988)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
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