Osteogenic capacity of cultured human periosteal cells
DOI:
https://doi.org/10.3109/17453678809149339Abstract
We developed a culture system of cells isolated from juvenile human periosteum. The culture consisted of epithelial-like and fibroblast-like cells. Both types of cells had intense alkaline phosphatase activity maintained in subculture. When these cells, loaded into diffusion chambers, were implanted subcutaneously in rats, cartilage tissue was mainly formed and bone was seen scantily. 1α-OH-D3 and 1,25-(OH)2-D3 increased the alkaline phosphatase activity and proteoglycan synthesis in the periosteal cells. Calcitonin also stimulated the proteoglycan synthesis, but parathyroid hormone had no effect.Downloads
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Published
1988-01-01
How to Cite
Uchida, A., Kikuchl, T., & Shimomura, Y. (1988). Osteogenic capacity of cultured human periosteal cells. Acta Orthopaedica, 59(1), 29–33. https://doi.org/10.3109/17453678809149339
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Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
