Short-term cefotaxime prophylaxis reduces the failure rate in lower limb amputations

Authors

  • Rolf Norlin
  • Aril Fryden
  • Lennart Nilsson
  • Steffan Ånséhn

DOI:

https://doi.org/10.3109/17453679008993563

Abstract

The effect of prophylaxis with a broad-spectrum antibiotic agent in lower limb amputations was studied in a prospective, randomized investigation of 38 patients. Nineteen received cefotaxime (Claforan®) and 19 served as controls. Three patients died in the immediate post-operative period. In the treatment group, 15/18 healed compared with 10/17 controls (P < 0.001). We concluded that short-term cefotaxime prophylaxis increases the chances to achieve good stump healing.

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Published

1990-01-01

How to Cite

Norlin, R., Fryden, A., Nilsson, L., & Ånséhn, S. (1990). Short-term cefotaxime prophylaxis reduces the failure rate in lower limb amputations. Acta Orthopaedica, 61(5), 460–462. https://doi.org/10.3109/17453679008993563