No effect of systemic administration of somatomedin C on bone repair in rats
DOI:
https://doi.org/10.3109/17453679008993530Abstract
The effect of somatomedin C on the bone repair process was studied in a rat femoral osteotomy. We used continuous systemic administration of human recombinant somatomedin C (110 μg/100 g per day). Radiographic evaluation after 4 weeks showed no effect of somatomedin C on the healing. There was no effect on mechanical strength, and no effect was found on callus vascularization or mineralization. The weight of the callus was slightly reduced in the somatomedin C treated rats. The results were not suggestive of any acceleration with systemic somatomedin C treatment in the early phase of cortical bone repair.Downloads
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Published
1990-01-01
How to Cite
Kirkeby, O. J., & Ekeland, A. (1990). No effect of systemic administration of somatomedin C on bone repair in rats. Acta Orthopaedica, 61(4), 335–338. https://doi.org/10.3109/17453679008993530
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Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
