Benzylpenicillin ineffective for open fractures: Prospective study of 60 cases

Authors

  • Seppo Vainionpää
  • Jarkko Vasenius
  • Pentti Rokkanen

DOI:

https://doi.org/10.3109/17453679009006511

Abstract

In a prospective study of 60 open fractures treated with prophylactic antibiotics, 10 developed infection with 2/40 Grades 1 and 2 fractures and 8/20 Grade 3 fractures. Intravenous penicillin was ineffective against Staphylococcus aureus and epidermidis, the most usual organisms causing infection in open fractures, as 62 percent of the organisms cultured from the initial culture and 92 percent of those cultured during infection were resistant to penicillin. For the second generation cephalosporins, the respective figures were 21 and 30 percent.

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Published

1990-01-01

How to Cite

Vainionpää, S., Vasenius, J., & Rokkanen, P. (1990). Benzylpenicillin ineffective for open fractures: Prospective study of 60 cases. Acta Orthopaedica, 61(2), 158–160. https://doi.org/10.3109/17453679009006511

Issue

Acta Orthopaedica, Volume 61, Issue 2 (1990)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
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