The effect of hyaluronic acid on cartilage in the immobilized rabbit knee
DOI:
https://doi.org/10.3109/17453679108994462Abstract
Out of 30 adult rabbits, 20 had one knee immobilized with a plaster of Paris cast for 6 or 12 weeks, and 10 rabbits were used as untreated controls. Prior to immobilization, 10 knees were injected with high-molecular weight hyaluronic acid. The articular cartilage of the femoral condyles was studied by light microscopy, whereas that of the patella and tibia was analyzed biochemically. Degenerative changes of the articular cartilage similar to those seen in arthrosis were observed after 6 weeks. The intraarticular injection of hyaluronic acid did not prevent these changes; instead, the reparative processes seemed inhibited.Downloads
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Published
1991-01-01
How to Cite
Olsenl, E. B., Trier, K., Jørgensen, B., Brok, K.-E., & Ammitzbøll, T. (1991). The effect of hyaluronic acid on cartilage in the immobilized rabbit knee. Acta Orthopaedica, 62(4), 323–326. https://doi.org/10.3109/17453679108994462
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Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
