Dehydration inhibits matrix synthesis and cell proliferation: An in vitro study of rabbit flexor tendons

Authors

  • Sven-Olof Abrahamsson
  • L.Stefan Lohmander
  • Göran Lundborg

DOI:

https://doi.org/10.3109/17453679108999247

Abstract

Segments of the deep flexor tendon of the rabbit were exposed to air; the effects of dehydration on in vitro synthesis of proteoglycan, collagen, non-collagenous protein, and cell proliferation were compared with tendon segments that were kept moist with physiologic saline. After 20 min of expo-sure to air, the tendons lost half and after 40 min all of their ability to synthesize matrix components and to proliferate, whereas irrigated tendons remained viable during the entire experiment.

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Published

1991-01-01

How to Cite

Abrahamsson, S.-O., Lohmander, L., & Lundborg, G. (1991). Dehydration inhibits matrix synthesis and cell proliferation: An in vitro study of rabbit flexor tendons. Acta Orthopaedica, 62(2), 159–162. https://doi.org/10.3109/17453679108999247