Effect of platelet derived growth factor on heterotopic bone formation in rats

Authors

  • Olof Risto
  • Ola Wahlström
  • Avni Abdiu
  • Thomas Waiz

DOI:

https://doi.org/10.3109/17453679108993090

Abstract

Platelet derived growth factor (PDGF) and induction of newly woven bone growth were studied in rats. PDGF (20 ng/mL) was administered continuously for 2 weeks via microosmotic pumps to 6-mm-long pieces of demineralized rat femur inserted into muscle pouches. Each rat had a control piece of demineralized bone inserted into the contralateral gluteal muscle. The samples were collected after 4 weeks, and wet and ash weight were recorded. Fourteen rats were evaluated. There were no differences as regards wet weights. PDGF increased the ash weights.

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Published

1991-01-01

How to Cite

Risto, O., Wahlström, O., Abdiu, A., & Waiz, T. (1991). Effect of platelet derived growth factor on heterotopic bone formation in rats. Acta Orthopaedica, 62(1), 49–51. https://doi.org/10.3109/17453679108993090