Calcitonin effects on rabbit bone

Authors

  • Theofilos Karachalios
  • George P Lyritis
  • Dionyssis G Giannarakos
  • George Papanicolaou
  • Kostas Sotopoulos

DOI:

https://doi.org/10.1080/17453679209169720

Abstract

30 adult male New Zealand white rabbits underwent osteotomy and plate fixation of the left ulna for 6 or 12 weeks. The right ulna served as control. In half of the rabbits 6 IU calcitonin was given daily until death, and in the other half placebo injections in the same manner. A three-point bending test was performed on both ulnae. Sections of bone, covered or uncovered by the plates, were examined histologically. Long-term administration of calcitonin increased the mechanical properties of both fractured and intact bones and reduced porosity of the cortex under the plate.

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Published

1992-01-01

How to Cite

Karachalios, T., Lyritis, G. P., Giannarakos, D. G., Papanicolaou, G., & Sotopoulos, K. (1992). Calcitonin effects on rabbit bone. Acta Orthopaedica, 63(6), 615–618. https://doi.org/10.1080/17453679209169720

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