Biodegradable guide for bone regeneration

Authors

  • Frank Farsø Nielsen
  • Thorkild Karring
  • Sylwester Gogolewski

DOI:

https://doi.org/10.3109/17453679209154853

Abstract

Segmental, 1-cm osteoperiosteal defects were produced in both radii of 10 rabbits. One defect was covered with a biodegradable polyurethane membrane formed as a tube. The contralateral defect served as an untreated control. Healing was analyzed by radiographic and histologic studies after 5 weeks. Nine out of 10 control defects displayed nonunion, whereas membrane-treated defects consistently healed by forming callus external to the membrane fusing the bone fragments. Loose connective tissue was predominant in the bone gap underneath the membrane.

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Published

1992-01-01

How to Cite

Nielsen, F. F., Karring, T., & Gogolewski, S. (1992). Biodegradable guide for bone regeneration. Acta Orthopaedica, 63(1), 66–69. https://doi.org/10.3109/17453679209154853