Enhancement of bone formation in rabbits by recombinant human growth hormone

Authors

  • Anders Ehrnberg
  • Otte Brosjö
  • Peter Låftman
  • Olle Nilsson
  • Lennart Strömberg

DOI:

https://doi.org/10.3109/17453679308993693

Abstract

We studied the effect of human recombinant growth hormone on diaphyseal bone in 40 adult rabbits. The diaphyseal periosteum of one femur in each animal was mechanically stimulated by a nylon cerclage band. The bands induced an increase in bone formation, bone mineral content, and maximum torque capacity of the diaphyseal bone at 1 and 2 months. Growth hormone enhanced the anabolic effect of the cerclage bands on bone metabolism, evidenced by a further increase in torsional strength of the femurs.

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Published

1993-01-01

How to Cite

Ehrnberg, A., Brosjö, O., Låftman, P., Nilsson, O., & Strömberg, L. (1993). Enhancement of bone formation in rabbits by recombinant human growth hormone. Acta Orthopaedica, 64(5), 562–566. https://doi.org/10.3109/17453679308993693

Issue

Acta Orthopaedica, Volume 64, Issue 5 (1993)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
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