No irregular erythrocyte antibodies observed after bone allografts in 144 patients
DOI:
https://doi.org/10.3109/17453679308993643Abstract
Red cell blood group antigens present in bone allografts may cause the formation of irregular erythrocyte antibodies (IEA). In the literature, 4 such cases have been described; all were Rh(D) negative females who had received Rh(D) positive bone and had made anti-Rh(D). To investigate the immunization by red cells after bone allografting, a retrospective and a prospective study was carried out. Altogether 144 patients were tested for the presence of IEA, before as well as after obtaining frozen allogeneic bone in orthopedic or maxillo-facial surgery. In 9 patients, the tests disclosed IEA preoperatively. No new IEA were detected postoperatively in the 144 patients, including 30 Rh(D) negative patients who received Rh(D) positive bone. We conclude that formation of IEA is a rare phenomenon. Nevertheless, it is recommended to give only Rh(D) negative bone to Rh(D) negative girls and women of childbearing age.Downloads
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Published
1993-01-01
How to Cite
Stassen, J. G. M., van Dijk, B. A., van Horn, J. R., & Kunst, V. A. J. M. (1993). No irregular erythrocyte antibodies observed after bone allografts in 144 patients. Acta Orthopaedica, 64(3), 354–356. https://doi.org/10.3109/17453679308993643
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Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
