Chondrocyte behavior in fibrin glue in vitro

Authors

  • George N Homminga
  • Pieter Buma
  • Henk W J Koot
  • Peter M van der Kraan
  • Wim B van den Berg

DOI:

https://doi.org/10.3109/17453679308993663

Abstract

To test fibrin glue as a vehicle in chondrocyte transplantation, chondrocytes, isolated from articular cartilage of young rabbits, were mixed with Tissucol®, a highly concentrated fibrin glue, and cultured for 7 days. Histology, autoradiography (35-S) and electron microscopy were used to study chondrocyte behavior and phenotypic expression. Chondrocytes multiplied, retained their morphology, and produced matrix in fibrin glue as long as the cells were surrounded by the glue. Glue disintegration started after 3 days and was accelerated by higher cell concentrations.

Downloads

Download data is not yet available.

Downloads

Published

1993-01-01

How to Cite

Homminga, G. N., Buma, P., Koot, H. W. J., van der Kraan, P. M., & van den Berg, W. B. (1993). Chondrocyte behavior in fibrin glue in vitro. Acta Orthopaedica, 64(4), 441–445. https://doi.org/10.3109/17453679308993663

Issue

Acta Orthopaedica, Volume 64, Issue 4 (1993)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
Crossref
Scopus
Google Scholar
Europe PMC