Distribution of CMP and COMP in human cartilage

Authors

  • Nik Hauser
  • Jana Geiss
  • Michel Neidhart
  • Mats Paulsson
  • Hans Jörg Häuselmann

DOI:

https://doi.org/10.3109/17453679509157652

Abstract

Cartilage matrix protein (CMP) is a noncollagenous glycoprotein with a molecular mass of 148 kDa consisting of three identical subunits linked together at their C-terminal assembly domains via a coiled-coil α-helix (Hauser and Paulsson 1994). Electron microscopy of the native protein showed trimers with compact ellipsoid subunits, each consisting of two von Willebrand factor A-domains linked via one EGF-like repeat. CMP is a highly insoluble protein which appears to become covalently crosslinked within the cartilage matrix with maturation.

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Published

1995-01-01

How to Cite

Hauser, N., Geiss, J., Neidhart, M., Paulsson, M., & Häuselmann, H. J. (1995). Distribution of CMP and COMP in human cartilage. Acta Orthopaedica, 66(sup266), 72–73. https://doi.org/10.3109/17453679509157652