Effect of time interval on tissue concentrations of cephalosporins after tourniquet inflation: Highest levels achieved by administration 20 minutes before inflation

Eleftherios Dounis; Stephanos Tsourvakas; Lambros Kalivas; Helen Giamacellou

doi:10.3109/17453679508995512

Effect of time interval on tissue concentrations of cephalosporins after tourniquet inflation: Highest levels achieved by administration 20 minutes before inflation

Authors

Eleftherios Dounis
Stephanos Tsourvakas
Lambros Kalivas
Helen Giamacellou

DOI:

https://doi.org/10.3109/17453679508995512

Abstract

We studied the effect of different time intervals between antibiotic administration and tourniquet inflation in 62 patients undergoing reconstructive surgery in the lower extremities. The in vivo concentrations in soft tissue and bone of 3 cephalosporins (ceftazidime, ceftriaxone and ceforanide) were determined. Our findings suggest that the highest tissue concentrations were achieved by administration 20 min before tourniquet inflation.

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Published

1995-01-01

How to Cite

Dounis, E., Tsourvakas, S., Kalivas, L., & Giamacellou, H. (1995). Effect of time interval on tissue concentrations of cephalosporins after tourniquet inflation: Highest levels achieved by administration 20 minutes before inflation. Acta Orthopaedica, 66(2), 158–160. https://doi.org/10.3109/17453679508995512

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Issue

Acta Orthopaedica, Volume 66, Issue 2 (1995)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.