Increased interleukin-6 in collected drainage blood after total knee arthroplasty: An association with febrile reactions during retransfusion

Authors

  • Martin Handel
  • Jochen Winkler
  • Rainer F Hörnlein
  • Hinnak Northoff
  • Peter Heeg
  • Martin Teschner
  • Stefan Sell

DOI:

https://doi.org/10.1080/00016470152846600

Abstract

We determined interleukin-6 (IL-6) concentrations in collected shed drainage blood intended for retransfusion in a prospective study in 81 patients after total knee replacement. We found large increases in IL-6 levels, averaging 6.5 (SD 3.9) ng/mL, in shed blood collected in the first 6 postoperative hours. 3 patients had febrile reactions after collected blood was retransfused. The IL-6 levels in the drainage blood of these patients were very high (9.6-13.4 ng/mL). In the blood collected after 6 hours, IL-6 concentrations increased to 47 (SD 33) ng/mL (p < 0.001). These results suggest a relation between increased interleukin-6 concentrations in shed drainage blood and the occurrence of febrile reactions after retransfusion of such blood.

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Published

2001-01-01

How to Cite

Handel, M., Winkler, J., Hörnlein, R. F., Northoff, H., Heeg, P., Teschner, M., & Sell, S. (2001). Increased interleukin-6 in collected drainage blood after total knee arthroplasty: An association with febrile reactions during retransfusion. Acta Orthopaedica, 72(3), 270–272. https://doi.org/10.1080/00016470152846600

Issue

Acta Orthopaedica, Volume 72, Issue 3 (2001)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
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