Soft-tissue sarcoma of the thigh: Surgical margin influences local recurrence but not survival in 152 patients

Authors

  • Søren Vraa
  • Johnny Keller
  • Ole Steen Nielsen
  • Anne Grethe Jurik
  • Olaf Myhre Jensen

DOI:

https://doi.org/10.1080/000164701753606734

Abstract

Between 1979 and 1998, 152 patients with a soft-tissue sarcoma arising in the thigh were surgically treated in the Sarcoma Center in Aarhus, Denmark. We studied clinicopathologic factors prognostic for local recurrence and survival. 27 patients (18%) had a low-grade tumor, 26 (17%) an intermediate-grade and 99 (65%) a high-grade tumor. 27 patients (18%) were amputated and 125 (82%) had a local resection. 21 (14%) underwent a marginal resection, 82 (54%) a wide resection and 49 (32%) a compartmental resection. 32 patients were also given radiotherapy, 11 of these had a marginal resection. The 5-year local recurrence-free rate was 91%. Multivariate analysis selected marginal resection and histological high grade as unfavorable prognostic factors for local recurrence. The 5-year survival rate was 68%. High age and histological high grade were unfavorable prognostic factors for survival in a multivariate analysis. Surgical margin influenced local recurrence, but not the overall survival.

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Published

2001-01-01

How to Cite

Vraa, S., Keller, J., Nielsen, O. S., Jurik, A. G., & Jensen, O. M. (2001). Soft-tissue sarcoma of the thigh: Surgical margin influences local recurrence but not survival in 152 patients. Acta Orthopaedica, 72(1), 72–77. https://doi.org/10.1080/000164701753606734

Issue

Acta Orthopaedica, Volume 72, Issue 1 (2001)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.
 
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