Incorporation of vancomycin-supplemented bone allograftsRadiographical, histopathological and immunohistochemical study in pigs

Martín Buttaro; Alejandro González Della Valle; Laura Piñeiro; Esteban Mocetti; Ana Morandi; Francisco Piccaluga

doi:10.1080/00016470310017884

Incorporation of vancomycin-supplemented bone allograftsRadiographical, histopathological and immunohistochemical study in pigs

Authors

Martín Buttaro
Alejandro González Della Valle
Laura Piñeiro
Esteban Mocetti
Ana Morandi
Francisco Piccaluga

DOI:

https://doi.org/10.1080/00016470310017884

Abstract

We compared the incorporation of bone allografts with or without vancomycin in tibial defects of 18 pigs. High-quality radiographs, histological examination, immunological expression of metalloproteinase-13 (MMP-13) and transforming growth factor-beta 2 (TGFß2) indicated that there was no significant difference in bone allograft incorporation between up to 220 times the MIC (minimum inhibitory concentration) in bone allografts with 1 g of vancomycin in each 300 g of allograft or without this supplement.

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Published

2003-01-01

How to Cite

Buttaro, M., González Della Valle, A., Piñeiro, L., Mocetti, E., Morandi, A., & Piccaluga, F. (2003). Incorporation of vancomycin-supplemented bone allograftsRadiographical, histopathological and immunohistochemical study in pigs. Acta Orthopaedica, 74(5), 505–513. https://doi.org/10.1080/00016470310017884

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Issue

Acta Orthopaedica, Volume 74, Issue 5 (2003)

Section

Articles

License

Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.