Staples, tension-band plates, and percutaneous epiphysiodesis screws used for leg-length discrepancy treatment: a systematic review and proportional meta-analysis

Authors

  • Maria Tirta Interdisciplinary Orthopedics, Aalborg University Hospital
  • Mette Holm Hjorth Department of Orthopedics Surgery, Aarhus University Hospital
  • Jette Frost Jepsen Medical Library, Aalborg University Hospital, Denmark
  • Søren Kold Interdisciplinary Orthopedics, Aalborg University Hospital https://orcid.org/0000-0002-3387-1473
  • Ole Rahbek Interdisciplinary Orthopedics, Aalborg University Hospital https://orcid.org/0000-0002-5602-4533

DOI:

https://doi.org/10.2340/17453674.2024.41104

Keywords:

Epiphysiodesis, Knee, LLD, Paediatric orthopaedics

Abstract

Background and purpose: The primary aim of this systematic review and meta-analysis was to evaluate the success rate of 3 different epiphysiodesis techniques with implant usage for the treatment of leg-length discrepancy (LLD) in the pediatric population. The secondary aim was to address effectiveness (final LLD) and the reported complications of staples, tension-band plates (TBP), and percutaneous epiphysiodesis screws (PETS).
Methods: In this systematic review we searched MEDLINE (PubMed), Embase, Cochrane Library, Web of Science and Scopus for studies on skeletally immature patients with LLD treated with epiphysiodesis with an implant. The extracted outcome categories were effectiveness of epiphysiodesis (LLD measurements pre-/postoperatively, successful/unsuccessful) and complications that were graded on severity.
Results: 44 studies (2,184 patients) were included. 455 underwent epiphysiodesis with PETS, 578 patients with TBP, and 1,048 with staples. Successful epiphysiodesis was reported in 76% (95% confidence interval [CI] 61–89) with PETS (9 studies), 67% (CI 54–79) with TBP (10 studies), and 51% (CI 28–65) with Blount staples (8 studies). From pooled analysis, the severe complications rate was 7% for PETS, 17% for TBP, and 16% for Blount staples. Angular deformity was reported in 4% after PETS, 10% after TBP, and 17% after Blount staples.
Conclusion: Our results showed that epiphysiodesis with PETS implants was the most successful technique. PETS had a higher success rate, fewer severe complications, and a lower proportion with angular deformity.

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References

Ruzbarsky J J, Goodbody C, Dodwell E. Closing the growth plate: a review of indications and surgical options. Curr Opin Pediatr 2017; 29(1): 80-6. doi: 10.1097/MOP.0000000000000438. DOI: https://doi.org/10.1097/MOP.0000000000000438

Blount W P, Clarke G R. Control of bone growth by epiphyseal stapling; a preliminary report. J Bone Joint Surg Am 1949; 31(3): 464-78. DOI: https://doi.org/10.2106/00004623-194931030-00002

Gorman T M, Vanderwerff R, Pond M, MacWilliams B, Santora S D. Mechanical axis following staple epiphysiodesis for limb-length inequality. J Bone Joint Surg Am 2009; 91(10): 2430-9. doi: 10.2106/JBJS.H.00896. DOI: https://doi.org/10.2106/JBJS.H.00896

Stevens P. Guided growth: 1933 to the present. Strateg Trauma Limb Reconstr 2006; 1: 29-35. doi: 10.1007/s11751-006-0003-3. DOI: https://doi.org/10.1007/s11751-006-0003-3

Gottliebsen M, Shiguetomi-Medina J M, Rahbek O, Møller-Madsen B. Guided growth: mechanism and reversibility of modulation. J Child Orthop 2016;10(6):471-477. doi: 10.1007/s11832-016-0778-9. DOI: https://doi.org/10.1007/s11832-016-0778-9

Metaizeau J P, Wong-Chung J, Bertrand H, Pasquier P. Percutaneous epiphysiodesis using transphyseal screws (PETS). J Pediatr Orthop 1998; 18(3): 363-9. DOI: https://doi.org/10.1097/01241398-199805000-00018

Lykissas M G, Jain V V, Manickam V, Nathan S, Eismann E A, McCarthy J J. Guided growth for the treatment of limb length discrepancy: a comparative study of the three most commonly used surgical techniques. J Pediatr Orthop B 2013; 22(4): 311-17. doi: 10.1097/BPB.0b013e32836132f0. DOI: https://doi.org/10.1097/BPB.0b013e32836132f0

Cheng Y-H, Lee W-C, Tsai Y-F, Kao H-K, Yang W-E, Chang C-H. Tension band plates have greater risks of complications in temporary epiphysiodesis. J Child Orthop 2021; 15: 106-13. doi: 10.1302/1863-2548.15.200180. DOI: https://doi.org/10.1302/1863-2548.15.200180

Page M J, McKenzie J E, Bossuyt P M, Boutron I, Hoffmann T C, Mulrow C D et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Syst Rev 2021; 10: 89. doi: 10.1136/bmj.n71. DOI: https://doi.org/10.1136/bmj.n71

Black S R, Kwon M S, Cherkashin A M, Samchukov M L, Birch J G, Jo C H. Lengthening in congenital femoral deficiency: a comparison of circular external fixation and a motorized intramedullary nail. J Bone Joint Surg Am 2015; 97(17): 1432-40. doi: 10.2106/JBJS.N.00932 DOI: https://doi.org/10.2106/JBJS.N.00932

Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J. Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg 2003; 73(9): 712-16. doi:10.1046/j.1445-2197.2003.02748.x. DOI: https://doi.org/10.1046/j.1445-2197.2003.02748.x

Stevens P, Desperes M, McClure P K, Presson A, Herrick J. Growth deceleration for limb length discrepancy: tension band plates followed to maturity. Strategies Trauma Limb Reconstr 2022; 17(1): 26-31. doi: 10.5005/jp-journals-10080-1548. DOI: https://doi.org/10.5005/jp-journals-10080-1548

Tolk J J, Merchant R, Calder P R, Hashemi-Nejad A, Eastwood D M. Tension-band plating for leg-length discrepancy correction. Strategies Trauma Limb Reconstr 2022; 17(1): 19-25. doi: 10.5005/jp-journals-10080-1547. DOI: https://doi.org/10.5005/jp-journals-10080-1547

Demirel M, Sağlam Y, Yıldırım A M, Bilgili F, Şeker A, Şen C. Temporary epiphysiodesis using the eight-plate in the management of children with leg length discrepancy: a retrospective case series. Indian J Orthop 2022; 56(5): 874-882. doi: 10.1007/s43465-021-00599-9. DOI: https://doi.org/10.1007/s43465-021-00599-9

Erdal O A, Gorgun B, Razi O, Sarikaya I A, Inan M. Effects of tension band plating on coronal plane alignment of lower extremities in children treated for idiopathic limb length discrepancy. J Child Orthop 2022; 16(6): 505-11. doi: 10.1177/18632521221135192. DOI: https://doi.org/10.1177/18632521221135192

Petrova D A, Kenis V M. Assessment of comparative parameters of leg length discrepancy in children using temporary epiphysiodesis with 8-plates. Ped Traum Orthop Rec Surg 2022; 10(2): 151-60. doi: 10.17816/PTORS104405. DOI: https://doi.org/10.17816/PTORS104405

Ozdemir E, Cetik R M, Ayvaz M, Yilmaz G. The efficacy of two-hole tension band plates in the treatment of lower extremity limb length discrepancy. J Pediatr Orthop B 2022; 31(1): e31-e36. doi: 10.1097/BPB.0000000000000861. DOI: https://doi.org/10.1097/BPB.0000000000000861

De Pellegrin M, Brogioni L, Laskow G, Barera G, Pajno R, Osimani S, et al. Guided growth in leg length discrepancy in Beckwith-Wiedemann Syndrome: a consecutive case series. Children (Basel) 2021; 8(12): 1152. doi: 10.3390/children8121152. DOI: https://doi.org/10.3390/children8121152

Masquijo J, Allende V, Artigas C, Hernández Bueno J C, Morovic M, Sepúlveda M. Partial hardware removal in guided growth surgery: a convenient strategy? Rev Esp Cir Ortop Traumatol (Engl Ed) 2021; 65(3): 195-200. doi: 10.1016/j.recot.2020.09.003. DOI: https://doi.org/10.1016/j.recote.2021.02.004

Sinha R, Weigl D, Mercado E, Becker T, Kedem P, Bar-On E. Eight-plate epiphysiodesis: are we creating an intra-articular deformity? Bone Joint J 2018; 100-B(8): 1112-16. doi: 10.1302/0301-620X.100B8.BJJ-2017-1206.R3. DOI: https://doi.org/10.1302/0301-620X.100B8.BJJ-2017-1206.R3

Joeris A, Ramseier L, Langendörfer M, von Knobloch M, Patwardhan S, Dwyer J, et al. Paediatric lower limb deformity correction with the Eight Plate: adverse events and correction outcomes of 126 patients from an international multicentre study. J Pediatr Orthop B 2017; 26(5): 441-8. doi: 10.1097/BPB.0000000000000397. DOI: https://doi.org/10.1097/BPB.0000000000000397

Gaumétou E, Mallet C, Souchet P, Mazda K, Ilharreborde B. Poor efficiency of eight-plates in the treatment of lower limb discrepancy. J Pediatr Orthop 2016; 36(7): 715-19. doi: 10.1097/BPO.0000000000000518. DOI: https://doi.org/10.1097/BPO.0000000000000518

Jochymek J, Peterková T. [Eight-plate guided growth treatment for angular deformities and length discrepancies of the lower limbs in children:. our first experience]. Acta Chir Orthop Traumatol Cech 2015; 82(6): 424-9. DOI: https://doi.org/10.55095/achot2015/070

Pendleton A M, Stevens P M, Hung M. Guided growth for the treatment of moderate leg-length discrepancy. Orthopedics 2013; 36(5):e575-80. doi: 10.3928/01477447-20130426-18. DOI: https://doi.org/10.3928/01477447-20130426-18

Dodwell E R, Garner M R, Bixby E, Luderowski E M, Green D W, Blanco J S, et al. Percutaneous epiphysiodesis using transphyseal screws: a case series demonstrating high efficacy. HSS J 2017; 13(3): 255-62. doi: 10.1007/s11420-017-9549-5. DOI: https://doi.org/10.1007/s11420-017-9549-5

Song M H, Choi E S, Park M S, Yoo W J, Chung C Y, Choi I H, et al. Percutaneous epiphysiodesis using transphyseal screws in the management of leg length discrepancy: optimal operation timing and techniques to avoid complications. J Pediatr Orthop 2015; 35(1): 89-93. doi: 10.1097/BPO.0000000000000214. DOI: https://doi.org/10.1097/BPO.0000000000000214

Monier B C, Aronsson D D, Sun M. Percutaneous epiphysiodesis using transphyseal screws for limb-length discrepancies: high variability among growth predictor models. J Child Orthop 2015; 9(5): 403-10. doi: 10.1007/s11832-015-0687-3. DOI: https://doi.org/10.1007/s11832-015-0687-3

Ilharreborde B, Gaumetou E, Souchet P, Fitoussi F, Presedo A, Penneçot G F, et al. Efficacy and late complications of percutaneous epiphysiodesis with transphyseal screws. J Bone Joint Surg Br 2012; 94(2): 270-5. doi: 10.1302/0301-620X.94B2.27470. DOI: https://doi.org/10.1302/0301-620X.94B2.27470

Khoury J G, Tavares J O, McConnell S, Zeiders G, Sanders J O. Results of screw epiphysiodesis for the treatment of limb length discrepancy and angular deformity. J Pediatr Orthop 2007; 27(6): 623-8. doi: 10.1097/BPO.0b013e318093f4f4. DOI: https://doi.org/10.1097/BPO.0b013e318093f4f4

Nouth F, Kuo L A. Percutaneous epiphysiodesis using transphyseal screws (PETS): prospective case study and review. J Pediatr Orthop 2004; 24(6): 721-5. DOI: https://doi.org/10.1097/01241398-200411000-00023

Skyttä E, Savolainen A, Kautiainen H, Lehtinen J, Belt E A. Treatment of leg length discrepancy with temporary epiphyseal stapling in children with juvenile idiopathic arthritis during 1957–99. J Pediatr Orthop 2003; 23(3): 378-80. DOI: https://doi.org/10.1097/01241398-200305000-00019

Raab P, Wild A, Seller K, Krauspe R. Correction of length discrepancies and angular deformities of the leg by Blount’s epiphyseal stapling. Eur J Pediatr 2001; 160(11): 668-74. doi: 10.1007/s004310100834. DOI: https://doi.org/10.1007/s004310100834

Sengupta A, Gupta P. Epiphyseal stapling for leg equalization in developing countries. Int Orthop 1993; 17(1): 37-42. doi: 10.1007/BF00195222. DOI: https://doi.org/10.1007/BF00195222

Watillon M, Hoet F. [Epiphyseal stapling in the treatment of leg length inequality]. Acta Orthop Belg 1986; 52(2): 209-16.

Mukherji D, Das A K. Epiphyseal stapling for the correction of lower limb inequality following poliomyelitis. Indian J Orthop 1979; 13(1): 17-22.

Cabalzar A. [Experiences with temporary epiphyseal stapling by Blount]. Z Orthop Ihre Grenzgeb 1978; 116(3): 355-62.

May V R Jr, Clements E L. Epiphyseal stapling: with special reference to complications. South Med J 1965; 58(10): 1203-7. doi: 10.1097/00007611-196510000-00002. DOI: https://doi.org/10.1097/00007611-196510000-00002

Cohen L L, Shore B J, Miller P E, Troy M J, Mahan S T, Kasser J R, et al. Epiphysiodesis for leg length discrepancy: a cost analysis of drill versus screw technique. J Surg Orthop Adv 2021; 30(3) :181-4.

Borbas P, Agten C A, Rosskopf A B, Hingsammer A, Eid K, Ramseier L E. Guided growth with tension band plate or definitive epiphysiodesis for treatment of limb length discrepancy? J Orthop Surg Res 2019; 14(1): 99. doi: 10.1186/s13018-019-1139-4. DOI: https://doi.org/10.1186/s13018-019-1139-4

Troy M, Shore B, Miller P, Mahan S, Hedequist D, Heyworth B, et al. A comparison of screw versus drill and curettage epiphysiodesis to correct leg-length discrepancy. J Child Orthop 2018; 12(5): 509-14. doi: 10.1302/1863-2548.12.180030. DOI: https://doi.org/10.1302/1863-2548.12.180030

Bayhan I A, Karatas A F, Rogers K J, Bowen J R, Thacker M M. Comparing percutaneous physeal epiphysiodesis and eight-plate epiphysiodesis for the treatment of limb length discrepancy. J Pediatr Orthop 2017; 37(5): 323-7. doi: 10.1097/BPO.0000000000000647. DOI: https://doi.org/10.1097/BPO.0000000000000647

Babu L V, Evans O, Sankar A, Davies A G, Jones S, Fernandes J A. Epiphysiodesis for limb length discrepancy: a comparison of two methods. Strategies Trauma Limb Reconstr 2014; 9(1): 1-3. doi: 10.1007/s11751-013-0180-9. DOI: https://doi.org/10.1007/s11751-013-0180-9

Stewart D, Cheema A, Szalay E A. Dual 8-plate technique is not as effective as ablation for epiphysiodesis about the knee. J Pediatr Orthop 2013; 33(8): 843-6. doi: 10.1097/BPO.0b013e3182a11d23. DOI: https://doi.org/10.1097/BPO.0b013e3182a11d23

Campens C, Mousny M, Docquier P L. Comparison of three surgical epiphysiodesis techniques for the treatment of lower limb length discrepancy. Acta Orthop Belg 2010; 76(2): 226-32.

Frediani P, Nocivelli P, Capilupi P. [Role of epiphysiodesis in the treatment of leg length inequality]. Chir Organi Mov 1987; 72: 221–6.

Younis M H, Hanstein R, Javed K, Fornari E D, Gomez J A, Sharkey M S, et al. Percutaneous epiphysiodesis using transphyseal screws (PETS) versus tension-band plating (TBP): comparative study of outcomes for correcting limb length discrepancy. Eur J Orthop Surg Traum 2023; 33(5): 1523-31. doi: 10.1007/s00590-022-03304-0. DOI: https://doi.org/10.1007/s00590-022-03304-0

Vogt B, Roedl R, Gosheger G, Frommer A, Laufer A, Kleine-Koenig M T, et al. Growth arrest: leg length correction through temporary epiphysiodesis with a novel rigid staple (RigidTack). Bone Joint J 2021; 103-B(8): 1428-37. doi: 10.1302/0301-620X.103B8.BJJ-2020-1035.R4. DOI: https://doi.org/10.1302/0301-620X.103B8.BJJ-2020-1035.R4

Frommer A, Niemann M, Gosheger G, Eveslage M, Toporowski G, Laufer A, et al. Temporary proximal tibial epiphysiodesis for correction of leg length discrepancy in children: should proximal fibular epiphysiodesis be performed concomitantly? J Clin Med 2021; 10(6): 1245. doi: 10.3390/jcm10061245. DOI: https://doi.org/10.3390/jcm10061245

Lee W C, Kao H K, Yang W E, Chang C H. Tension band plating is less effective in achieving equalization of leg length. J Child Orthop 2018; 12(6): 629-34. doi: 10.1302/1863-2548.12.170219. DOI: https://doi.org/10.1302/1863-2548.12.170219

Corradin M, Schiavon R, Borgo A, Deslandes J, Cersosimo A, Canavese F. The effects of uninvolved side epiphysiodesis for limb length equalization in children with unilateral cerebral palsy: clinical evaluation with the Edinburgh visual gait score. Eur J Orthop Surg Traumatol 2018; 28: 977–84. doi: 10.1007/s00590-017-2097-3. DOI: https://doi.org/10.1007/s00590-017-2097-3

Siedhoff M, Ridderbusch K, Breyer S, Stücker R, Rupprecht M. Temporary epiphysiodesis for limb-length discrepancy: 8- to 15-year follow-up of 34 children. Acta Orthop 2014; 85(6): 626-32. doi: 10.3109/17453674.2014.960646. DOI: https://doi.org/10.3109/17453674.2014.960646

Bylander B, Hansson L I, Selvik G. Pattern of growth retardation after Blount stapling: a roentgen stereophotogrammetric analysis. J Pediatr Orthop 1983; 3(1): 63-72. doi: 10.1097/01241398-198302000-00011. DOI: https://doi.org/10.1097/01241398-198302000-00011

Tirta M, Hjorth M H, Jepsen J F, Rahbek O, Kold S. Are percutaneous epiphysiodesis and Phemister technique effective in the treatment of leg-length discrepancy? A systematic review. J Pediatr Orthop B 2024. doi: 10.1097/BPB.0000000000001160. DOI: https://doi.org/10.1097/BPB.0000000000001160

Published

2024-07-18

How to Cite

Tirta, M., Hjorth, M. H., Jepsen, J. F., Kold, S., & Rahbek, O. (2024). Staples, tension-band plates, and percutaneous epiphysiodesis screws used for leg-length discrepancy treatment: a systematic review and proportional meta-analysis. Acta Orthopaedica, 95, 415–424. https://doi.org/10.2340/17453674.2024.41104

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