The influence of night-time bracing on curve progression is not affected by curve magnitude in adolescent idiopathic scoliosis: a study of 299 patients
DOI:
https://doi.org/10.2340/17453674.2024.39965Abstract
Background and purpose: The efficacy of bracing larger curves in adolescent idiopathic scoliosis (AIS) patients is uncertain. We aimed to assess the influence of night-time bracing in AIS patients with main curves exceeding 40° Cobb angle at brace initiation.
Methods: We reviewed AIS patients treated with nighttime braces between 2005 and 2018. Patients with curves ≥ 25° and estimated growth potential were included. Patients were monitored with radiographs from brace initiation until brace weaning at skeletal maturity. Patients were grouped based on curve magnitude at initial evaluation: a control group (25–39°) and a large-curves group (≥ 40°). Progression was defined as > 5° increase.
Results: We included 299 patients (control group, n = 125; large-curves group, n = 174). In the control group, 65 (52%) patients progressed compared with 101 (58%) in the large-curves group (P = 0.3). The lower-end vertebra (LEV) shifted distally post-bracing in 41 (23%) patients in the largecurves group. Patients with progressive large curves were younger (age 13.2 [SD 1.5] vs. 13.9 [SD 1.1], P = 0.009) and more premenarchal (n = 36 [42%] vs. n = 6 [9%], P < 0.001) compared with non-progressive large curves.
Conclusion: Progression risk in patients with curves exceeding 40° treated with night-time bracing is similar to smaller curves. The LEV moved distally in almost one-fourth of the larger curves, possibly affecting fusion levels in cases of surgery.
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Richards B S, Bernstein R M, D’Amato C R, Thompson G H. Standardization of criteria for adolescent idiopathic scoliosis brace studies. Spine 2005; 30(18): 2068-75. doi: 10.1097/01.brs.0000178819.90239.d0. DOI: https://doi.org/10.1097/01.brs.0000178819.90239.d0
Weinstein S L, Dolan L A, Cheng J C Y, Danielsson A, Morcuende J A. Adolescent idiopathic scoliosis. Lancet 2008; 371(9623): 1527-37. doi: 10.1016/S0140-6736(08)60658-3. DOI: https://doi.org/10.1016/S0140-6736(08)60658-3
Ahn H, Kreder H, Mahomed N, Beaton D, Wright J G. Empirically derived maximal acceptable wait time for surgery to treat adolescent idiopathic scoliosis. CMAJ 2011; 183(9): E565-70. doi: 10.1503/cmaj.101511. DOI: https://doi.org/10.1503/cmaj.101511
Oksanen H, Lastikka M, Helenius L, Pajulo O, Helenius I. Posterior spinal fusion extended to stable vertebra provides similar outcome in juvenile idiopathic scoliosis patients compared with adolescents with fusion to the touched vertebra. Scand J Surg 2019; 108(1): 83-9. doi: 10.1177/1457496918798193. DOI: https://doi.org/10.1177/1457496918798193
Sponseller P D, Jain A, Newton P O, Lonner B S, Shah S A, Shufflebarger H, et al. Posterior spinal fusion with pedicle screws in patients with idiopathic scoliosis and open triradiate cartilage: does deformity progression occur? J Pediatr Orthop 2016; 36(7): 695-700. doi: 10.1097/BPO.0000000000000524. DOI: https://doi.org/10.1097/BPO.0000000000000524
Newton P O, Bartley C E, Bastrom T P, Kluck D G, Saito W, Yaszay B. Anterior spinal growth modulation in skeletally immature patients with idiopathic scoliosis. J Bone Joint Surg Am 2020; 102(9): 769-77. doi: 10.2106/JBJS.19.01176. DOI: https://doi.org/10.2106/JBJS.19.01176
Hrustic A, Vujadinovic A, Isakovic E, Delic J. Crankshaft phenomenon in patients operated for adolescent idiopathic scoliosis. Global Spine J 2015; 5 (1_suppl): s-0035-1554249. doi: 10.1055/s-0035-1554249. DOI: https://doi.org/10.1055/s-0035-1554249
Ohrt-Nissen S, Luk K D K, Samartzis D, Cheung J P Y. Selection of the lowest instrumented vertebra in main thoracic adolescent idiopathic scoliosis: is it safe to fuse shorter than the last touched vertebra? Eur Spine J 2020; 29(8): 2018-24. doi: 10.1007/s00586-020-06398-4. DOI: https://doi.org/10.1007/s00586-020-06398-4
Cho R H, Yaszay B, Bartley C E, Bastrom T P, Newton P O. Which Lenke 1A curves are at the greatest risk for adding-on … and why? Spine 2012; 37(16): 1384-90. doi: 10.1097/BRS.0b013e31824bac7a. DOI: https://doi.org/10.1097/BRS.0b013e31824bac7a
Weinstein S L, Dolan L A, Wright J G, Dobbs M B. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med 2013; 369(16): 1512-21. doi: 10.1056/NEJMoa1307337. DOI: https://doi.org/10.1056/NEJMoa1307337
Maillot C, Ferrero E, Fort D, Heyberger C, Le Huec J-C. Reproducibility and repeatability of a new computerized software for sagittal spinopelvic and scoliosis curvature radiologic measurements: Keops®. Eur Spine J 2015; 24(7): 1574-81. doi: 10.1007/s00586-0153817-1. DOI: https://doi.org/10.1007/s00586-015-3817-1
Sanders J O, Khoury J G, Kishan S, Browne R H, Mooney J F, Arnold K D, et al. Predicting scoliosis progression from skeletal maturity: a simplified classification during adolescence. J Bone Joint Surg Am 2008 ; 90(3): 540-53. doi: 10.2106/JBJS.G.00004. DOI: https://doi.org/10.2106/JBJS.G.00004
von Elm E, Altman D G, Egger M, Pocock S J, Gøtzsche P C, Vandenbroucke J P. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies. Bull World Health Organ 2007; 5(11): 867-72. doi: 10.2471/BLT.07.045120. DOI: https://doi.org/10.2471/BLT.07.045120
Negrini S, Donzelli S, Aulisa A G, Czaprowski D, Schreiber S, de Mauroy J C, et al. 2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth. Scoliosis Spinal Disord 2018; 13(1): 3. doi: 10.1186/s13013-017-0145-8. DOI: https://doi.org/10.1186/s13013-017-0145-8
Ruffilli A, Fiore M, Barile F, Pasini S, Faldini C. Evaluation of nighttime bracing efficacy in the treatment of adolescent idiopathic scoliosis: a systematic review. Spine Deform 2021; 9(3): 671-8. doi: 10.1007/s43390-020-00248-5. DOI: https://doi.org/10.1007/s43390-020-00248-5
Verhofste B P, Whitaker A T, Glotzbecker M P, Miller P E, Karlin L I, Hedequist D J, et al. Efficacy of bracing in skeletally immature patients with moderate–severe idiopathic scoliosis curves between 40° and 60°. Spine Deform 2020; 8(5): 911-20. doi: 10.1007/s43390-020-00131-3. DOI: https://doi.org/10.1007/s43390-020-00131-3
Razeghinezhad R, Kamyab M, Babaee T, Ganjavian M S, Bidari S. The effect of brace treatment on large curves of 40° to 55° in adolescents with idiopathic scoliosis who have avoided surgery: a retrospective cohort study. Neurospine 2021; 18(3): 437-44. doi: 10.14245/ns.2040654.327. DOI: https://doi.org/10.14245/ns.2040654.327
Katz D E, Durrani A A. Factors that influence outcome in bracing large curves in patients with adolescent idiopathic scoliosis. Spine 2001; 26(21): 2354-61. doi: 10.1097/00007632-200111010-00012. DOI: https://doi.org/10.1097/00007632-200111010-00012
Wiley J W, Thomson J D, Mitchell T M, Smith B G, Banta J V. Effectiveness of the Boston brace in treatment of large curves in adolescent idiopathic scoliosis. Spine 2000; 25(18): 2326-32. doi: 10.1097/00007632200009150-00010. DOI: https://doi.org/10.1097/00007632-200009150-00010
Negrini S, Negrini F, Fusco C, Zaina F. Idiopathic scoliosis patients with curves more than 45 Cobb degrees refusing surgery can be effectively treated through bracing with curve improvements Spine J 2011; 11(5): 369-80. doi: 10.1016/j.spinee.2010.12.001. DOI: https://doi.org/10.1016/j.spinee.2010.12.001
Lusini M, Donzelli S, Minnella S, Zaina F, Negrini S. Brace treatment is effective in idiopathic scoliosis over 45°: an observational prospective cohort controlled study Spine J 2014; 14(9): 1951-6. doi: 10.1016/j.spinee.2013.11.040. DOI: https://doi.org/10.1016/j.spinee.2013.11.040
Simony A, Beuschau I, Quisth L, Jespersen S M, Carreon L Y, Andersen M O. Providence nighttime bracing is effective in treatment for adolescent idiopathic scoliosis even in curves larger than 35°. Eur Spine J 2019; 28(9): 2020-4. doi: 10.1007/s00586-019-06077-z. DOI: https://doi.org/10.1007/s00586-019-06077-z
Ohrt-Nissen S, Hallager D W, Gehrchen M, Dahl B. Flexibility predicts curve progression in Providence nighttime bracing of patients with adolescent idiopathic scoliosis. Spine 2016; 41(22): 1724-30. doi: 10.1097/BRS.0000000000001634. DOI: https://doi.org/10.1097/BRS.0000000000001634
Yagci G, Demirkiran G, Yakut Y. In-brace alterations of pulmonary functions in adolescents wearing a brace for idiopathic scoliosis. Prosthet Orthot Int 2019; 43(4): 434-9. doi: 10.1177/0309364619839856. DOI: https://doi.org/10.1177/0309364619839856
Badra M I, Feldman D S, Hart R A. Thoracic adolescent idiopathic scoliosis: selection of fusion level. J Pediatr Orthop B 2010; 19(5): 465-72. doi: 10.1097/BPB.0b013e32833cb72d. DOI: https://doi.org/10.1097/BPB.0b013e32833cb72d
Sanders J O, Browne R H, McConnell S J, Margraf S A, Cooney T E, Finegold D N. Maturity assessment and curve progression in girls with idiopathic scoliosis. J Bone Joint Surg Am 2007; 89(1): 64-73. doi: 10.2106/JBJS.F.00067. DOI: https://doi.org/10.2106/JBJS.F.00067
van den Bogaart M, van Royen B J, Haanstra T M, de Kleuver M, Faraj S S A. Predictive factors for brace treatment outcome in adolescent idiopathic scoliosis: a best-evidence synthesis. Eur Spine J 2019; 28(3): 511-25. doi: 10.1007/s00586-018-05870-6. DOI: https://doi.org/10.1007/s00586-018-05870-6
Heegaard M, Tøndevold N, Dahl B, Andersen T B, Gehrchen M, Ohrt-Nissen S. Does Risser stage accurately predict the risk of curve progression in patients with adolescent idiopathic scoliosis treated with night-time bracing? Eur Spine J 2023; 32(9): 3077-83. doi: 10.1007/s00586-023-07808-z. DOI: https://doi.org/10.1007/s00586-023-07808-z
Laquièvre A, Dolet N, Moisson L, Colobert B, Mallet J-F, Bronfen C. Compliance with night-time overcorrection bracing in adolescent idiopathic scoliosis: result from a cohort follow-up. Med Eng Phys 2020; 77: 137-41. doi: 10.1016/j.medengphy.2020.01.003. DOI: https://doi.org/10.1016/j.medengphy.2020.01.003
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Copyright (c) 2024 Martin Heegaard, Niklas Tøndevold, Benny Dahl, Thomas B Andersen, Martin Gehrchen, Søren Ohrt-Nissen
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