The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis
DOI:
https://doi.org/10.1080/000164701753532844Abstract
39 patients with active knee osteoarthrosis, chosen according to ACR criteria, were assigned to receive flurbiprofen (n 12, 2 2 100 mg), tiaprofenic acid (n 14, 2 2 300 mg) and placebo (n 13) in a 3-week, placebo-controlled study. All patients completed the study, and both medications were found to be effective: improvement occurred in the clinical signs. These drugs reduced the TNF- f levels. Flurbiprofen especially affected the IL-6 levels. Our findings indicate that NSAIDs may be effective in the etiopathogenesis of osteoarthrosis.Downloads
Download data is not yet available.
Downloads
Published
2001-01-01
How to Cite
Uzun, H., Tuzun, S., Ozaras, N., Aydin, S., Ozaras, R., Dondurmaci, S., & Tuzun, F. (2001). The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis. Acta Orthopaedica, 72(5), 499–502. https://doi.org/10.1080/000164701753532844
Issue
Section
Articles
License
Acta Orthopaedica (Scandinavica) content is available freely online as from volume 1, 1930. The journal owner owns the copyright for all material published until volume 80, 2009. As of June 2009, the journal has however been published fully Open Access, meaning the authors retain copyright to their work. As of June 2009, articles have been published under CC-BY-NC or CC-BY licenses, unless otherwise specified.